六氟并咪唑（CCI-103F）是一种低氧细胞标记物，可通过体内[1H]/[19F]磁共振光谱（MRS）测量。发现在SCCVII肿瘤中CCI-103F的保留与肿瘤大小相关，较大的肿瘤保留更多的标记。这种相关性是可以预期的，因为较大的SCCVII肿瘤具有较大的低氧部分。还发现CCI-103F保留量与10 Gy辐照后存活的肿瘤细胞比例之间也有显著但不强的相关性，保留更大量CCI-103F的肿瘤具有更高的存活比例。这些结果表明，无创的MRS测量CCI-103F保留能够预测SCCVII肿瘤的放射敏感性。然而，CCI-103F保留与放射敏感性之间的相关性不强表明，在这些肿瘤中，低氧部分并不是影响放射敏感性的唯一因素。

Hexafluoromisonidazole (CCI-103F) is a hypoxic cell label that can be measured by in vivo [1H]/[19F] magnetic resonance spectroscopy (MRS). The retention of CCI-103F in SCCVII tumors was found to be correlated with tumor size, with larger tumors retaining more label. Such a correlation was anticipated, as larger SCCVII tumors have larger hypoxic fractions. A significant but less strong correlation was also found between CCI-103F retention and the fraction of tumor cells surviving after 10 Gy irradiation, with tumors that retained larger amounts of CCI-103F having higher surviving fractions. These results indicated that non-invasive MRS measurement of CCI-103F retention could predict radiosensitivity in SCCVII tumors. The lack of a strong correlation between CCI-103F retention and radiosensitivity, however, indicated that hypoxic fraction was not the only factor influencing radiosensitivity in these tumors.