褐藻酸多酚化合物类——多酚类物质中一种基于海藻的物质——已被证明具有抗氧化、抗微生物、抗过敏、抗糖尿病、抗炎、抗癌、神经保护等潜在生物活性。这些生物活性进一步提高了全球市场需求，目前正在探索超临界流体萃取、微波辅助萃取、酶辅助萃取、利用深度共熔溶剂萃取等可持续技术生产富含褐藻酸多酚的提取物。尽管有这样充分的生物活性文献资料，但可商业化的褐藻酸多酚营养保健品很少，这凸显了关于它们生理益处的消费者意识生成具有重要意义。然而，对于产业化的准确量化来说，特别是针对不同类别的褐藻酸多酚量化，需要先进的分析技术，如质谱、1H-NMR光谱等，因为这些物质具有广泛的结构差异。本综述总结了基于体内和体外研究发现的褐藻酸多酚的萃取和生物活性。 © 作者（们），独家授权 Springer Nature B.V. 2022。

Phlorotannins, a seaweed based class of polyphenolic compounds, have proven to possess potential bioactivities such as antioxidant, antimicrobial, anti-allergic, anti-diabetic, anti-inflammatory, anti-cancerous, neuroprotection etc. These bioactivities have further increased demand globally and sustainable techniques such as supercritical fluid extraction, microwave assisted extraction, enzyme assisted extraction, extraction using deep eutectic solvents etc. are being explored currently for production of phlorotannin-rich extracts. In spite of such well documented bioactivities, very few phlorotannin-based nutraceuticals are available commercially which highlights the significance of generating consumer awareness about their physiological benefits. However, for industry level commercialization accurate quantification of phlorotannins with respect to the different classes is vital requiring sophisticated analytical techniques such as mass spectrometry, 1H-NMR spectroscopy etc. owing to the wide structural diversity. This review summarizes the extraction and bioactivities of phlorotannins based on the findings of in vivo and in vitro studies.© The Author(s), under exclusive licence to Springer Nature B.V. 2022.