基于纳米技术的电化学生物传感器用于监测乳腺癌生物标志物。
Nanotechnology-based electrochemical biosensors for monitoring breast cancer biomarkers.
发表日期:2022 Dec 04
作者:
Hassan Nasrollahpour, Balal Khalilzadeh, Mohammad Hasanzadeh, Reza Rahbarghazi, Pedro Estrela, Abdolhossein Naseri, Savas Tasoglu, Mika Sillanpää
来源:
MEDICINAL RESEARCH REVIEWS
摘要:
乳腺癌是全球妇女中最普遍的癌症类型。及时诊断可以通过正确的治疗程序降低死亡率。这些特点有助于减少药物治疗时间和社会经济负担。目前的综述文章提供了关于使用纳米材料和相关技术进行乳腺癌诊断的全面评估。详细讨论了纳米/生物技术领域在电化学纳米生物传感器设计方面的不断增长的应用。在这方面,针对放大生物传感方法应用于乳腺癌诊断的纳米材料的最新进展进行了评估,并着重讨论了这些方法的优缺点。我们还从统计学的角度监测设计方法、优势和适当(纳米)材料的必要性。这篇评论的主要目标是基于乳腺癌生物标志物分类适用的生物传感器。随着为乳腺癌诊断发布的许多纳米平台,这篇综述尝试收集最适合检测生物标志物和某些乳腺癌细胞类型的方法。© 2022 Wiley Periodicals LLC.
Breast cancer is categorized as the most widespread cancer type among women globally. On-time diagnosis can decrease the mortality rate by making the right decision in the therapy procedure. These features lead to a reduction in medication time and socioeconomic burden. The current review article provides a comprehensive assessment for breast cancer diagnosis using nanomaterials and related technologies. Growing use of the nano/biotechnology domain in terms of electrochemical nanobiosensor designing was discussed in detail. In this regard, recent advances in nanomaterial applied for amplified biosensing methodologies were assessed for breast cancer diagnosis by focusing on the advantages and disadvantages of these approaches. We also monitored designing methods, advantages, and the necessity of suitable (nano) materials from a statistical standpoint. The main objective of this review is to classify the applicable biosensors based on breast cancer biomarkers. With numerous nano-sized platforms published for breast cancer diagnosis, this review tried to collect the most suitable methodologies for detecting biomarkers and certain breast cancer cell types.© 2022 Wiley Periodicals LLC.