前列腺磁共振成像（MRI）现在已成为评估疑似前列腺癌（PCa）的标准。基于MRI的多种方法已彻底改变了前列腺活检的方式。本研究描述了一种新颖的Vector MRI/超声融合经会阴穿刺（TP）活检技术的步骤，展示了该技术在局部麻醉（LA）下使用电磁（EM）针追踪技术的准确性和耐受性。我们在2020年9月至2022年8月间，在英国的两个中心对符合活检标准的69名患者进行了BiopSee融合软件、EM追踪技术和经直肠超声的Vector前列腺活检。我们将安装了步进马达的直肠超声图像与MRI扫描进行融合。在两个预定义的会阴通道内注射局麻药，插入带有EM传感器的穿刺套管，通过EM追踪精确地引导活检针到MRI目标处进行活检。没有进行抗生素预防性治疗的前提下进行了活检。记录了癌症检测（任何PCa; 等级组别≥2）、副作用和患者体验指标。对于Likert 4-5病灶的患者，任何PCa的癌症检测率为98％，等级组别≥2的检测率为83％。根据返回的50份调查问卷，42名患者（84％）表示没有或很少疼痛，而40名患者（80％）表示没有或很少不适。没有出现术后尿潴留的情况，仅有一名患者需要治疗感染。该研究的局限性包括患者数量较少和问卷回复不完整，但总体而言，这种新颖的 Vector 技术提供了一种可行和耐受的MRI/超声融合TP活检程序，具有较高的癌症检测率，同时保持患者的舒适性和最低的并发症率。 我们报告了一种新的技术，使用电磁针追踪在局部麻醉下经会阴穿刺进行前列腺活检，可以高度准确且舒适。 © 2022年欧洲泌尿科协会。由Elsevier B.V.发表，版权所有。

Prostate magnetic resonance imaging (MRI) is now standard for assessment of suspected prostate cancer (PCa). A variety of approaches to MRI-based targeting has revolutionised prostate biopsies.To describe the procedure and show the accuracy and tolerability of a novel Vector MRI/ultrasound fusion transperineal (TP) biopsy technique that uses electromagnetic (EM) needle tracking under local anaesthesia (LA).Vector prostate biopsy using BiopSee fusion software, EM tracking technology, and transrectal ultrasound was performed in 69 patients meeting the biopsy criteria in two UK centres between September 2020 and August 2022.Stepper-mounted rectal ultrasound images were fused with MRI scans. LA was applied into two defined perineal tracks and a needle sheath with an EM sensor was inserted. The biopsy needle was directed precisely through the sheath to MRI targets under EM tracking. Biopsies were taken without antibiotic prophylaxis.Cancer detection (any PCa; grade group ≥2), side effects, and patient experience measures were recorded.Cancer detection in patients with Likert 4-5 lesions was 98% for any PCa and 83% for grade group ≥2. According to the 50 questionnaires returned, 42 patients (84%) reported no or minimal pain, while 40 (80%) reported no or minimal discomfort. No episodes of postoperative urinary retention occurred, and only one patient required treatment for infection. Limitations include the low patient number and incomplete responses to questionnaires.This novel Vector technique provides a feasible and tolerable procedure for MRI/ultrasound fusion TP biopsy under LA, with high cancer detection rates. This is achieved while maintaining patient comfort and with minimal rates of complications.We report a novel technique that uses electromagnetic needle tracking to perform highly accurate and comfortable prostate biopsies through the perineum under local anaesthetic.Copyright © 2022 European Association of Urology. Published by Elsevier B.V. All rights reserved.