Effect of nano-curcumin on various diseases: A comprehensive review of clinical trials. 纳米姜黄素对各种疾病的作用：临床试验的全面回顾。
Effect of nano-curcumin on various diseases: A comprehensive review of clinical trials.
发表日期：2023 Jan 06
作者：
Shirin Hassanizadeh, Mehrnaz Shojaei, Mohammad Bagherniya, Alexander N Orekhov, Amirhossein Sahebkar
来源：
BIOFACTORS
摘要：
姜黄素具有抗氧化、抗炎和抗菌特性，因此成为改善COVID-19、癌症、抑郁症、焦虑症、骨关节炎、偏头痛和糖尿病等各种疾病的有价值的草药产品。最近的研究表明，将姜黄素封装在纳米粒子中可能会提高其治疗效果和生物利用度。据我们所知，有关纳米姜黄素在健康和疾病不同方面的疗效尚未进行总结性研究。因此，本文旨在根据临床试验的研究结果，评估纳米姜黄素在各种疾病中的疗效性。为了审查有关纳米姜黄素在各种疾病中的影响的出版物，我们搜索了四个数据库，包括PubMed、Scopus、Web of Science和Google学术。本文强调了纳米姜黄素在改善COVID-19、神经系统疾病、慢性疾病、口腔疾病、骨关节炎、代谢综合症和其他疾病中的潜在益处，特别是作为标准治疗和健康生活方式的辅助治疗。©2023年国际生物化学和分子生物学联盟。
The antioxidant, anti-inflammatory, and antibacterial properties of curcumin have made it a valuable herbal product for improving various disorders, such as COVID-19, cancer, depression, anxiety, osteoarthritis, migraine, and diabetes. Recent research has demonstrated that encapsulating curcumin in nanoparticles might improve its therapeutic effects and bioavailability. To our knowledge, the efficacy of nano-curcumin on different aspects of health and disease has not been summarized in a study. Therefore, this review aimed to evaluate nano-curcumin's efficacy in various diseases based on the findings of clinical trials. In order to review publications focusing on nanocurcumin's impact on various diseases, four databases were searched, including PubMed, Scopus, Web of Science, and Google Scholar. This review highlights the potential benefits of nano-curcumin in improving a wide range of human diseases including COVID-19, neurological disorders, chronic disease, oral diseases, osteoarthritis, metabolic syndrome, and other diseases, especially as an adjunct to standard therapy and a healthy lifestyle.© 2023 International Union of Biochemistry and Molecular Biology.