内窥镜监测Barrett食管，目的是为了检测常见的异型增生和腺癌，随后进行有效的内窥镜治疗，这是食管腺癌预防范式不可或缺的一部分。 然而，许多限制因素，比如异型增生的微妙表现、采样误差（存在于当前监测方案中）以及不遵守监测建议，都会导致错过异型增生和新生增生，降低当前监测方式的有效性。 仔细的内窥镜评估，采用高分辨率的白光内窥镜、染料或电子色素内窥镜以及对BE黏膜进行全面采样，仍然是内窥镜监测的基石。 由分子标记驱动的新兴创新方法涵盖了更高效的采样方法、先进的成像工具、人工智能以及辅助预测常见和预测异常增生或腺癌的方法。 开发和实施验证的质量指标将允许这一关键领域的进一步发展。 这些方法有望实现高效和有效的癌症防治。版权 © 2023 AGA协会。由Elsevier Inc.出版。保留所有权利。

Endoscopic surveillance of Barrett's esophagus, aiming to detect prevalent dysplasia and adenocarcinoma, followed by effective endoscopic treatment, is an integral part of the esophageal adenocarcinoma prevention paradigm. However, several limitations, such as the subtle appearance of dysplasia, sampling error (inherent in current surveillance protocols), and noncompliance with surveillance recommendations, lead to missed dysplasia and neoplasia, reducing the effectiveness of surveillance as currently practiced. Careful endoscopic assessment with high-resolution white-light endoscopy, dye-based or electronic chromoendoscopy, and comprehensive sampling of the BE mucosa, remains the cornerstone of endoscopic surveillance. Emerging innovations in this area span the gamut of more efficient sampling methods, advanced imaging tools, artificial intelligence, and molecular marker-powered approaches as adjuncts, to identify prevalent and predict incident dysplasia or adenocarcinoma. Development and implementation of validated quality indicators will allow additional advancement of this critical field. These approaches will hopefully enable efficient and effective cancer prevention and treatment.Copyright © 2023 AGA Institute. Published by Elsevier Inc. All rights reserved.