社区贫困与精神分裂症和双相情感障碍患者死亡率之间的关联——一项全国性随访研究。
Association between neighborhood deprivation and mortality in patients with schizophrenia and bipolar disorder-A nationwide follow-up study.
发表日期:2023 Feb 08
作者:
Filip Jansåker, Jan Sundquist, Kristina Sundquist, Xinjun Li
来源:
BIPOLAR DISORDERS
摘要:
翻译:目的是探索社区贫困与精神分裂症和躁郁症患者的全因死亡率和特定死亡率之间的关联。更好地理解这种潜在关系可能有助于确定具有增加死亡风险的精神分裂症和躁郁症患者。这项全国性研究包括所有接受精神分裂症(n = 34,544)和躁郁症(n = 64,035)诊断的成年人(≥30岁)在瑞典(1997-2017)进行。使用Cox回归分析探讨社区贫困与死亡率之间的关联。所有模型都在男女之间进行,调整了个体社会经济因素和并发症。两组中最常见的死因是冠心病和癌症。当社区贫困程度增加时,冠心病死亡率增加,并且在生活在最贫困社区的精神分裂症患者和躁郁症患者中达到了1.37(1.18-1.60)和1.70(1.44-2.01) 。这项研究显示,社区贫困是精神分裂症和躁郁症患者的全因死亡率和大多数特定死亡率的重要风险因素。这些发现可以成为决策者在分配医疗资源时和遇到这些条件下的患者的临床医生的帮助。 ©2023年作者。John Wiley&Sons Ltd发表的躁郁症杂志
The aim was to explore the association between neighborhood deprivation and all-cause mortality and cause-specific mortalities in patients with schizophrenia and bipolar disorder. A better understanding of this potential relationship may help to identify patients with schizophrenia and bipolar disorder with an increased mortality risk.This nationwide study included practically all adults (≥30 years) diagnosed with schizophrenia (n = 34,544) and bipolar disorder (n = 64,035) in Sweden (1997-2017). The association between neighborhood deprivation and mortality was explored using Cox regression. All models were conducted in both men and women and adjusted for individual-level sociodemographic factors and comorbidities.There was an association between level of neighborhood deprivation and all-cause mortality in both groups. The adjusted hazard ratios for all-cause mortality associated with high compared to low neighborhood deprivation were 1.18 (95% confidence interval 1.11-1.25) in patients with schizophrenia and 1.33 (1.26-1.41) in patients with bipolar disorder. The two most common mortality causes in both groups were coronary heart disease and cancer. The mortality due to coronary heart disease increased when neighborhood deprivation increased and reached 1.37 (1.18-1.60) in patients with schizophrenia and 1.70 (1.44-2.01) in patients with bipolar disorder living in the most deprived neighborhoods.This study shows that neighborhood deprivation is an important risk factor for all-cause mortality and most cause-specific mortalities among patients with schizophrenia and bipolar disorder. These findings could serve as aid to policymakers when allocating healthcare resources and to clinicians who encounter patients with these conditions in deprived neighborhoods.© 2023 The Authors. Bipolar Disorders published by John Wiley & Sons Ltd.