研究动态
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“你的皮肤会告诉你”角化细胞癌宣传活动:个人选择的影响。

"Your Skin Tells You" Campaign for keratinocyte cancers: when individuals' selection makes the difference.

发表日期:2023 Feb 08
作者: Maria Concetta Fargnoli, Paolo Antonetti, Laura Atzori, Paolo Taddeucci, Alessandro Di Stefani, Vieri Grandi, Lucia Lospalluti, Francesco Lacarrubba, Sabina Vaccari, Paolo Amerio, Gabriella Fabbrocini, Mariateresa Rossi, Elena Campione, Raffaele Dante Caposiena Caro, Elvira Moscarella, Franco Rongioletti, Cristina Pellegrini, Ketty Peris, Discab
来源: DERMATOLOGY

摘要:

预防皮肤癌的运动主要集中在黑色素瘤上,随着时间的推移,人们越来越意识到需要选择筛查人群以最大程度地提高程序的有效性。为报告一项针对独立选择的个体的角质细胞癌预防倡议的结果,作为一项专注于角质细胞癌的意识倡导运动的一部分,针对城市。 在2021年5月22日至6月30日期间,在15个皮肤肿瘤专科医院举行了一天的皮肤科诊断,个人通过短问题调查被选拔。收集患者的人口统计学资料,可疑肿瘤的临床特征和切除的病变的组织病理学诊断。计算了任何皮肤癌、基底细胞癌(BCC)、表皮细胞癌(cSCC)和黑色素瘤的怀疑率、检测率和阳性预测值(PPV)。 总共有320位个体(男性56.9%;女性43.1%),年龄中位数为69.6(21-91岁)。总体上,患者中有65.9%被诊断为皮肤癌或癌前病变。任何皮肤癌的疑似率为28.7%(92/320),BCC的疑似率为22.8%(73/320),cSCC的疑似率为4.7%(15/320),黑色素瘤的疑似率为1.2%(4/320)。任何皮肤癌的检出率为23.4%(PPV 93.7%),BCC的检出率为18.1%(PPV 95.1%),cSCC的检出率为4.4%(PPV 93.3%),黑色素瘤的检出率为0.9%(PPV 75%)。 选择高风险个体进行早期检测是一种具有成本效益的方法,用于角质细胞癌的早期检测运动。 S. Karger AG, Basel.
Prevention campaigns for skin cancers have focused primarily on melanoma, and over time there has been increasing awareness of the need to select the population to be screened to maximize program effectiveness.To report the results of a free dermatological initiative, as part of an awareness campaign dedicated to keratinocyte cancers, targeting individuals pre-selected through a short questionnaire.One day of dermatological consultations was held at 15 dermato-oncology referral centers during May 22-June 30, 2021. For selection, individuals answered a telephone interview consisting of 7 yes/no questions on risk factors. Demographics, clinical characteristics of suspicious tumors and histopathologic diagnosis of excised lesions were collected. Suspicion rate, detection rate and positive predictive values (PPV) for any skin cancer, basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (cSCC) and melanoma, were calculated.A total of 320 individuals (56.9% males; 43.1% females) with a median age of 69.6 (range 21-91) years qualified for the screening initiative. Overall, skin cancers and precancerous lesions were diagnosed in 65.9% of the patients. Suspicion rate was 28.7% for any skin cancer (92/320), 22.8% for BCC (73/320), 4.7% for cSCC (15/320) and 1.2% for melanoma (4/320). Detection rate was 23.4% for any skin cancer (PPV 93.7%), 18.1% for BCC (PPV 95.1%), 4.4% for cSCC (PPV 93.3%) and 0.9% for melanoma (PPV 75%).Selection of individuals at high-risk is a cost-effective approach for early detection campaigns for keratinocyte cancers.S. Karger AG, Basel.