医用大麻的使用和接受度正在全球范围内上升。为了支持公共健康利益，需要与这个社区需求匹配的有关其使用、效果和安全性的证据。研究人员和公共卫生机构常常使用基于网络的用户生成数据来调查消费者的感知、市场力量、人口行为以及药物流行病学。本综述的目的是总结使用用户生成文本作为研究医用大麻或大麻作为药物使用的数据源的研究的发现。我们的目标是将社交媒体研究结果归类为医用大麻和描述社交媒体对使用医用大麻的消费者的作用。本综述的包含标准是述那些报道大麻作为药物分析的网络用户生成内容的原始研究和综述。我们从1974年1月到2022年4月搜索了MEDLINE、Scopus、Web of Science和Embase数据库。我们检查了42篇用英文发表的文章，发现消费者珍视他们在网上交换经验的能力，并倾向于依赖于基于网络的信息来源。关于大麻的讨论将该物质描绘为一种安全和自然的药物，能够帮助处理许多健康问题，包括癌症、睡眠障碍、慢性疼痛、阿片类物质成瘾、头痛、哮喘、肠病、焦虑、抑郁和创伤后应激障碍。这些讨论为研究人员提供了一个丰富的资源，以调查与医用大麻相关的消费者情感和经验，包括监测大麻的效果和不良事件，鉴于信息的偏见和经验常常让人持怀疑态度时需妥善地纳入考虑。大麻业的广泛基于网络的存在，加上社交媒体话语的对话性，导致信息丰富但潜在地有偏见，并且往往不受科学证据的充分支持。这个综述总结了社交媒体对医用大麻的使用说了什么，并讨论了卫生治理机构和专业人士面临的挑战，即利用基于网络的资源既向医用大麻使用者学习，又向消费者提供准确、及时和可靠的基于证据的健康信息。 ©Sedigh Khademi, Christine Mary Hallinan, Mike Conway, Yvonne Bonomo. 本文最初发表于《医疗互联网研究杂志》(https://www.jmir.org)，2023年2月27日。

The use and acceptance of medicinal cannabis is on the rise across the globe. To support the interests of public health, evidence relating to its use, effects, and safety is required to match this community demand. Web-based user-generated data are often used by researchers and public health organizations for the investigation of consumer perceptions, market forces, population behaviors, and for pharmacoepidemiology.In this review, we aimed to summarize the findings of studies that have used user-generated text as a data source to study medicinal cannabis or the use of cannabis as medicine. Our objectives were to categorize the insights provided by social media research on cannabis as medicine and describe the role of social media for consumers using medicinal cannabis.The inclusion criteria for this review were primary research studies and reviews that reported on the analysis of web-based user-generated content on cannabis as medicine. The MEDLINE, Scopus, Web of Science, and Embase databases were searched from January 1974 to April 2022.We examined 42 studies published in English and found that consumers value their ability to exchange experiences on the web and tend to rely on web-based information sources. Cannabis discussions have portrayed the substance as a safe and natural medicine to help with many health conditions including cancer, sleep disorders, chronic pain, opioid use disorders, headaches, asthma, bowel disease, anxiety, depression, and posttraumatic stress disorder. These discussions provide a rich resource for researchers to investigate medicinal cannabis-related consumer sentiment and experiences, including the opportunity to monitor cannabis effects and adverse events, given the anecdotal and often biased nature of the information is properly accounted for.The extensive web-based presence of the cannabis industry coupled with the conversational nature of social media discourse results in rich but potentially biased information that is often not well-supported by scientific evidence. This review summarizes what social media is saying about the medicinal use of cannabis and discusses the challenges faced by health governance agencies and professionals to make use of web-based resources to both learn from medicinal cannabis users and provide factual, timely, and reliable evidence-based health information to consumers.©Sedigh Khademi, Christine Mary Hallinan, Mike Conway, Yvonne Bonomo. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 27.02.2023.