组织工程的进步正在以飞快的速度发展，提供了新颖的方法和对正常细胞和组织稳态、疾病发病机制以及新的潜在治疗策略的认识。新技术的演变特别为该领域注入了活力，涵盖了从新的器官和器官结构技术到越来越复杂的成像方式的范围。这对肺生物学和疾病领域尤其重要，因为许多肺部疾病，包括慢性阻塞性肺病（COPD）和特发性纤维化（IPF）等，仍然无法治愈，具有重要的发病率和死亡率。肺再生医学和工程的进展也为像急性呼吸窘迫综合征（ARDS）这样的关键疾病提供了新的潜在途径，该疾病仍然具有重要的发病率和死亡率。在这篇综述中，将呈现肺部再生医学的概述，重点关注当前结构和功能修复的现状。这将作为调查创新模型和技术的平台，凸显这些方法的必要性和及时性。版权所有 ©2023 Weiss。

Advances in tissue engineering continue at a rapid pace and have provided novel methodologies and insights into normal cell and tissue homeostasis, disease pathogenesis, and new potential therapeutic strategies. The evolution of new techniques has particularly invigorated the field and span a range from novel organ and organoid technologies to increasingly sophisticated imaging modalities. This is particularly relevant for the field of lung biology and diseases as many lung diseases, including chronic obstructive pulmonary disease (COPD) and idiopathic fibrosis (IPF), among others, remain incurable with significant morbidity and mortality. Advances in lung regenerative medicine and engineering also offer new potential avenues for critical illnesses such as the acute respiratory distress syndrome (ARDS) which also continue to have significant morbidity and mortality. In this review, an overview of lung regenerative medicine with focus on current status of both structural and functional repair will be presented. This will serve as a platform for surveying innovative models and techniques for study, highlighting the need and timeliness for these approaches.Copyright © 2023 Weiss.