这项研究旨在评估饲料中磷（P）缺乏对黄河鲤（Cyprinus carpio haematopterus）的生长性能、肝脏脂代谢和抗氧化能力的影响。在这项研究中，随机选择72只健康的实验鱼（初始重量=12.0±0.1克[平均值±标准误]），分为两组，每组三次重复。这两组分别被喂养P充足或P缺乏的饲料8周。P缺乏的饲料显著降低了黄河鲤的特定生长率、饲料利用率和条件因子。食用P缺乏的饲料的鱼类血浆中三酰甘油、总胆固醇（T-CHO）和低密度脂蛋白胆固醇含量以及肝脏中T-CHO含量均高于食用P充足饲料的鱼类。此外，P缺乏饲料显著降低了肝脏和血浆中的过氧化氢酶活性水平，减少了谷胱甘肽含量，并增加了丙二醛含量。此外，饲料中的P缺乏显著下调了核红细胞2相关因子2和过氧化物酶体增殖物激活受体α的信使RNA表达，同时上调了肿瘤坏死因子α和脂肪酸合成酶的信使RNA表达。饲料中的磷缺乏降低了鱼类的生长性能，诱导了脂肪沉积和氧化应激，并损害了肝脏的健康。 © 2023年美国渔业学会。

The study aimed to evaluate the effects of phosphorus (P) deficiency in diets on growth performance, hepatic lipid metabolism, and antioxidant capacity in Yellow River Carp Cyprinus carpio haematopterus.In this study, 72 healthy experimental fish (initial weight = 12.0 ± 0.1 g [mean ± SE]) were randomly selected and distributed to two groups, with three replicates in each group. The groups were fed either a P-sufficient diet or a P-deficient diet for 8 weeks.The P-deficient feed significantly decreased the specific growth rate, feed efficiency, and condition factor of Yellow River Carp. Fish that were fed the P-deficient feed demonstrated higher contents of triglyceride, total cholesterol (T-CHO), and low-density lipoprotein cholesterol in the plasma and a higher T-CHO content in the liver compared to the P-sufficient diet group. In addition, the P-deficient diet significantly reduced the catalase activity level, decreased the glutathione content, and increased the malondialdehyde content in the liver and in the plasma. Furthermore, P deficiency in the diet significantly downregulated the messenger RNA expression of nuclear erythroid 2-related factor 2 and peroxisome proliferator-activated receptor α, whereas it upregulated the messenger RNA expression of tumor necrosis factor α and fatty acid synthase in the liver.Dietary P deficiency reduced fish growth performance, induced fat deposition and oxidative stress, and impaired liver health.© 2023 American Fisheries Society.