COVID-19疫苗接种对癌症患者和细胞治疗接受者的影响。
COVID-19 Vaccination in Patients With Cancer and Recipients of Cellular Therapy.
发表日期：2023 Feb 24
作者：
Fareed Khawaja, Marilyne Daher, Amy Spallone, Roy F Chemaly
来源：
Cellular & Molecular Immunology
摘要：
COVID-19因患者体内免疫系统受损而继续不成比例地影响着癌症患者。缓解COVID-19对癌症患者的影响的策略包括接种疫苗，其已证明在一定程度上可提供保护，至少可防止严重并发症如呼吸功能衰竭和死亡，并存在一定安全性问题。在这篇叙述性评论文章中，我们讨论了目前在美国可用的COVID-19疫苗、已发表的癌症患者接种疫苗的功效和安全性的数据、目前的接种指南以及未来的方向。
COVID-19 continues to disproportionately affect patients with cancer because of their underlying immunocompromised state. Strategies to mitigate the impact of COVID-19 on patients with cancer include vaccination, which has demonstrated some level of protection, at least against serious complications such as respiratory failure and death, with limited safety concerns. In this narrative review, we discuss the current COVID-19 vaccines that are available in the United States, the published data regarding vaccine efficacy and safety in patients with cancer, current vaccination guidelines, and future directions.