来自不同天然来源的金属纳米颗粒相比传统方法展现出更优越的治疗选择。由于含有类黄酮、双黄酮、三萜类、类固醇、皂苷、单宁和其他次生代谢产物等生物活性分子，铁角蕨属植物吸引了全球研究人员的特别关注，这些分子展现出抗菌、抗疟疾、抗癌和抗炎活性。铁角蕨属植物环境友好型绿色合成的银纳米颗粒对抗不同真菌病原体提供了可行、安全和高效的治疗方式。本系统综述旨在总结使用铁角蕨属植物提取物绿色合成银纳米颗粒在抗真菌方面的优越能力相关文献的内容，与采用水和乙醇原植物提取物相比，通过电子收集数据库中的文章。在准备这篇综述时，我们考虑了首选报告项目的系统综述和荟萃分析的建议。根据纳入和排除标准，将收集到的数据的标题和摘要存储在Endnote20中。搜索策略包括了PubMed、Google Scholar和检索系统在线等已建立的来源文献，并使用主题词描述符。搜索结果共获得60篇具有独特命中度的文章。在去除重复之后，鉴定了46篇文章，评估了40篇并根据我们的资格标准选出了仅有的七篇文章，并将其纳入到这篇综述中。铁角蕨的物理化学和初步植物化学研究表明，与水和乙醇植物提取物相比，来自植物提取物合成的纳米颗粒对不同疾病具有更高的药物效力。该研究具有巨大的潜力，因为纳米颗粒的合成涉及的能源消耗低、技术需求较小且毒性作用最小。

Metallic nanoparticles from different natural sources exhibit superior therapeutic options as compared to the conventional methods. Selaginella species have attracted special attention of researchers worldwide due to the presence of bioactive molecules such as flavonoids, biflavonoids, triterpenes, steroids, saponins, tannins and other secondary metabolites that exhibit antimicrobial, antiplasmodial, anticancer and anti-inflammatory activities. Environment friendly green synthesised silver nanoparticles from Selaginella species provide viable, safe and efficient treatment against different fungal pathogens.This systematic review aims to summarise the literature pertaining to superior antifungal ability of green synthesised silver nanoparticles using plant extracts of Selaginella spp. in comparison to both aqueous and ethanolic raw plant extracts by electronically collecting articles from databases.The recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis were taken into consideration while preparing this review. The titles and abstracts of the collected data were stored in Endnote20 based on the inclusion and exclusion criteria. The search strategy included literature from established sources like PubMed, Google Scholar and Retrieval System Online using subject descriptors.The search yielded 60 articles with unique hits. After removal of duplications, 46 articles were identified, 40 were assessed and only seven articles were chosen and included in this review based on our eligibility criteria.The physicochemical and preliminary phytochemical investigations of Selaginella suggest higher drug potency of nanoparticles synthesised from plant extract against different diseases as compared to aqueous and ethanolic plant extracts. The study holds great promise as the synthesis of nanoparticles involves low energy consumption, minimal technology and least toxic effects.