增强型超声（CEUS）使用血管内对比剂以增强人体不同部位的血液流动信号，并评估微循环。过去十年间，CEUS在肌肉骨骼（MSK）医学领域的应用越来越广泛，本综述旨在系统总结CEUS在MSK领域的应用的最新研究，重点关注发表于2001年1月至2021年6月期间的67篇文章，这些文章在包括PubMed、Scopus和Embase等在线数据库中发表。CEUS已广泛用于肌肉微循环，肌腱病变，骨折不愈合，运动相关损伤，关节炎，外周神经和肿瘤的临床评估，并可作为预后和结局预测的客观和定量评估工具。每种疾病类别的最佳CEUS参数和诊断截断值仍需确认。版权：©2023《医学超声杂志》。

Contrast-enhanced ultrasound (CEUS) uses an intravascular contrast agent to enhance blood flow signals and assess microcirculation in different parts of the human body. Over the past decade, CEUS has become more widely applied in musculoskeletal (MSK) medicine, and the current review aims to systematically summarize current research on the application of CEUS in the MSK field, focusing on 67 articles published between January 2001 and June 2021 in online databases including PubMed, Scopus, and Embase. CEUS has been widely used for the clinical assessment of muscle microcirculation, tendinopathy, fracture nonunions, sports-related injuries, arthritis, peripheral nerves, and tumors, and can serve as an objective and quantitative evaluation tool for prognosis and outcome prediction. Optimal CEUS parameters and diagnostic cut off values for each disease category remain to be confirmed.Copyright: © 2023 Journal of Medical Ultrasound.