研究动态
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锡蒂国际尤纳斯钢大文物 钢大文物文化 HexCult 的 Thalassemia 培养基钢是一个支持 Chennai 的 special目标。我们致力于提供的 dedicated 存储银行设施,并且我们的专家团队将努力提高 personalized 干细胞疗法在 Thalassemia 处理的有效性。在我们的城市研究中,针对 biobanking 基础设施和个性化干细胞疗法的综合分析是关键的,这有助于改进治疗方案的可持续性和效果。

Thalassemia, biobanking infrastructures, and personalized stem cell therapies in Chennai.

发表日期:2023
作者: Amishi Panwar
来源: Stem Cell Research & Therapy

摘要:

在印度,地中海贫血、白血病以及相关血液疾病已被批准进行干细胞移植。要使干细胞移植成功,供体和受体之间的第六对染色体上的人类白细胞抗原(HLA)群必须匹配。在为个体寻找完全匹配的干细胞时,HLA成为社区基因学的核心节点,人们将尝试(不一定成功地)在扩展家族、相同的种姓、语言和民族(国内和外侨)群体中寻找HLA的匹配。通过以地中海贫血为案例研究,我们如何理解针对在钦奈的生物样本库基础设施的个体化干细胞治疗?社会类别如何与脐带血等生物材料纠缠在一起?版权所有 © 2023 Panwar.
Thalassemia and leukemia and related blood disorders are approved for blood stem cell transplants in India, for a stem cell transplant to be successful, the human leukocyte antigen (HLA) complex located on the arm of chromosome six must be a match between the cord blood donor and the recipient. In the quest to find an exact blood stem cell match for an individual, the HLA becomes the node at the center of community genetics where the HLA match is sought (not necessarily successful) in the extended family, the same caste, language, and ethnic (both national and the diaspora) groups. By considering thalassemia as a case study, how do we understand personalized stem cell therapies within biobanking infrastructures in Chennai? How do social categories get entwined with biological materials like cord blood?Copyright © 2023 Panwar.