经口机器人手术(TORS)在肿瘤学控制方面和放射治疗具有相同效果，但潜在提升生活质量（QOL）和降低患者对决策的后悔。本横断面研究纳入了2016年至2021年期间完成决策后悔量表（DRS）、M. D. Anderson吞咽困难评估表（MDADI）和华盛顿大学生活质量评定表（UW-QOL）的早期口咽癌患者。治疗结束至问卷完成的中位时间为1.8年(IQR 1.4-3.3, 范围1.0-5.6)。在65名患者中，84.6%的患者没有或只有轻微的决策后悔。决策后悔与临床参数或辅助治疗无关，但与MDADI(τavg = -0.23, p < 0.001)和UW-QOL(τavg = -0.27, p < 0.001)相关。较差的MDADI与年龄较大有关，而较差的UW-QOL与多部位手术和问卷填写时间较短有关。总体而言，TORS患者非常少表达决策后悔。DRS评分不受临床人口统计学或附加辅助疗法的影响，但决策后悔与较差的QOL和较差的吞咽有关。 版权所有 © 2023 Elsevier Ltd. 保留所有权利。

Transoral robotic surgery (TORS) has equivalent oncologic control to radiotherapy with potential for improved quality of life (QOL) and lower patient-reported decisional regret.Cross-sectional study between 2016 and 2021 of TORS patients with early-stage oropharyngeal squamous cell carcinoma who completed the Decision Regret Scale (DRS), M. D. Anderson Dysphagia Inventory (MDADI), and University of Washington Quality of Life (UW-QOL). The median time from treatment to questionnaire completion was 1.8 years (IQR 1.4-3.3, range 1.0-5.6).Of 65 patients, 84.6% expressed no or mild decisional regret. Regret was not associated with clinical parameters or adjuvant treatment but was correlated with MDADI (τavg = -0.23, p < 0.001) and UW-QOL (τavg = -0.27, p < 0.001). Worse MDADI was associated with older age and worse UW-QOL was associated with multi-site operation and shorter time to survey.Overall, the TORS cohort expressed very limited decisional regret. DRS scores were unaffected by clinicodemographics or additional adjuvant therapies, but decision regret was correlated with worse QOL and worse swallowing.Copyright © 2023 Elsevier Ltd. All rights reserved.