自从2000年代初广泛使用以来，阿达木单抗已被广泛用于银屑病和银屑病性关节炎的治疗。所有的肿瘤坏死因子抑制剂都被鉴定为药物诱导性红斑狼疮的致病因子，特别是依他妥单抗和英夫利昔单抗。有报道的阿达木单抗诱导系统性红斑狼疮的病例很少，更多的病例归因于依他妥单抗或英夫利昔单抗的治疗。我们在此报告一例患有长期银屑病和银屑病性关节炎的患者，其经阿达木单抗治疗取得了成功，但出现了抗肿瘤坏死因子诱发的红斑狼疮。© The Author(s) 2023.

Adalimumab is a tumor necrosis factor inhibitor that has been widely used since the early 2000s for the treatment of psoriasis and psoriatic arthritis. All tumor necrosis factor inhibitors have been identified as causative agents in drug induced lupus, particularly etanercept and infliximab. There have been few reported cases of systemic lupus erythematosus induced by adalimumab, many more are attributable to treatment with etanercept or infliximab. We present the case of a patient with long-standing psoriasis and psoriatic arthritis who was successfully treated with adalimumab, but developed anti-tumor necrosis factor-induced lupus.© The Author(s) 2023.