研究动态
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巴嗪醇在医学中的民族药用重要性:药理活性与分析方面

Ethnomedicinal importance of Patuletin in Medicine: Pharmacological Activities and Analytical Aspects.

发表日期:2023 Aug 16
作者: Dinesh Kumar Patel, Gireesh Kumar Singh, Gulam Mohammed Husain, Satyendra K Prasad
来源: ARTHRITIS RESEARCH & THERAPY

摘要:

植物衍生的生物活性分子一直是人类和兽医用途的主要治疗物质来源。全球不同传统医学体系一直依赖自然资源以满足其医疗需求。即使在现代世界中,制药行业也寻求植物化学物质来开发新药。本综述探讨了一种名为苦艾素的类黄酮化合物,以及其多样的已报道的药理活性和相关的分析技术。苦艾素的科学数据来自Scopus、Science Direct、Pubmed、Google和Google Scholar。收集到的数据经过分析并按照特定的药理活性及其在体外或体内实验中的表现进行整理。苦艾素的分析方法被呈现在药理活性之后。结果表明,现有的科学文献表明苦艾素具有抗炎、细胞毒、遗传毒性、肝脏保护、抗增殖、抗血小板、抗痛觉和抗氧化活性。除了这些活性外,本文还介绍了苦艾素在乳腺癌、类风湿性关节炎、醛还原酶和不同类型的微生物上的生物潜力。苦艾素的分析数据说明了其在草药产品和衍生药物标准化中的重要性。可以得出结论,苦艾素凭借其多样的生物活性和易得的分析方法,有潜力成为一种新的药物实体。版权所有© Bentham科学出版社,如有任何问题,请发送电子邮件至epub@benthamscience.net。
Plant-derived bioactive molecules have been a major source of therapeutics for human and veterinarian purposes. Different traditional medicine system across the globe had relied on natural resources to meet their demand of healthcare. Still in modern world pharmaceutical industries look for phytochemicals to develop new drugs. The current review explores patuletin, a flavonoid for its diverse reported pharmacological activities along with its analytical techniques.Scientific data published on patuletin was collected from Scopus, Science Direct, Pubmed, Google, and Google Scholar. The collected data were analyzed and arranged as per specific pharmacological activities performed using in-vitro or in-vivo methods. Analytical methods of patuletin have been presented next to pharmacological activities, Results: Available scientific literature indicates patuletin has anti-inflammatory, cytotoxic, genotoxic, hepatoprotective, antiproliferative, antiplatelet, antinociceptive, and antioxidant activity. In addition to these activities, its biological potential on breast cancer, rheumatoid arthritis, aldose reductase, and different types of microorganisms has been also presented in this work. Analytical data on patuletin signified the importance of patuletin for the standardization of herbal products and derived medicine.It may be concluded that patuletin with its diverse biological activities and readily available analytical methods, holds the potential to be translated into a new drug entity.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.