研究动态
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病例报告:巨大的折振溃疡伴随胸壁上马尔哲夫溃疡,合并严重的烧伤后颈部挛缩的管理困境。

A case report: Management dilemma in a large fungating squamous cell carcinoma over a Marjolin's ulcer on the chest wall coexisting with severe post burn contracture of the neck.

发表日期:2023 Jul 28
作者: Suruchi Sanjay, Aman Choudhary, Meena Kumari, Bharati Pandya, Vinay Kumar
来源: Burns & Trauma

摘要:

Marjolin溃疡是在疤痕和慢性炎症组织上发生的癌前病变。鳞状细胞癌是与Marjolin溃疡相关的最常见恶性肿瘤。这些是罕见的肿瘤,可以局部扩散,并且一旦浸润,可能会引发远处扩散。在我们的病例中,由于反复出血导致严重贫血和恶臭排液,要求早期切除,在这种情况下的问题是由于他的胸部状况和严重烧伤引起的颈部挛缩,他不适合全身麻醉。他接受了连续局部切除和随后连续皮片移植。我们呈现了一个病例,一个病人因胸部烧伤瘢痕以及烧伤后颈部挛缩而出现大量腐烂的鳞状细胞癌,由于插管问题在管理方面存在问题。由于这些疤痕上的瘢痕组织和有限的淋巴和血管供应,疾病和转移的进展相对较慢。由于复杂性和紧迫性,我们以非常规的局部麻醉下连续切除和创面皮片移植的方式进行了管理。在这种病例中,管理的一些改变可能会给患者带来新的生机,这是通过这个病例传达的信息。版权所有©2023 Elsevier Ltd.
Marjolin's ulcer is a premalignant condition occurring over scars and chronically inflamed tissue. Squamous cell carcinoma is the most common malignancy associated with Marjolin's ulcer. These are rare tumors which spread locally and once infiltrating, may lead to distant spread. In our case recurrent bleeding causing severe anaemia and foul smelling discharge, mandated an early resection, the problem in this case was due to his chest condition and severe post-burn neck contracture and he was unfit for general anesthesia. He was subjected to serial local excisions as well as subsequent serial skin grafts.We present a case of a large fungating squamous cell carcinoma in a patent having burn scar over his chest as well has having post-burn contracture of the neck, posing problems in management due to intubation issues.The progression of disease and metastasis is relatively slow due to scarring and meager lymphatic and vascular supply over these scars. Owing to the complexities and urgency, we managed him unconventionally with serial excision under local anesthesia and skin grafting of the wound.Some alterations in management may be a gift of life in such patients is the message through this case.Copyright © 2023. Published by Elsevier Ltd.