一名58岁的女性患者出现急性髓系异常增生性白血病（AML），并发双侧树突状上皮角膜炎，无视网膜炎。患者最初通过口服阿昔洛韦治疗，初步诊断为单纯疱疹病毒（HSV）角膜炎。通过软尖头拭子采集眼部分泌物样本进行聚合酶链反应（PCR），结果显示巨细胞病毒（CMV)感染。随后停用阿昔洛韦，通过静脉注射甘西气生治疗双侧CMV角膜炎，患者上皮损害逐渐消失。本病例报告证实CMV能够引起角膜上皮受损但无视网膜受累，并且示儿了CMV角膜炎是AML的紧急问题。因此，任何双侧角膜疱疹性炎症病例均应考虑免疫系统缺陷的评估。 版权声明：© 2023 阿曼眼科学会。

A 58-year-old woman presented with acute myeloblastic leukemia (AML) developed a bilateral dendritic epithelial keratitis without retinitis. The patient was initially treated with oral acyclovir with a possible diagnosis of herpes simplex virus (HSV) keratitis. Polymerase chain reaction (PCR) was performed on ocular discharge specimens collected by soft-tipped applicators reported as cytomegalovirus (CMV). Then, acyclovir was discontinued and bilateral CMV keratitis was treated with IV ganciclovir and her epithelial lesions gradually disappeared. The current case report confirms that CMV is capable of generating corneal epithelial engagement without retina involvement and demonstrated that CMV keratitis is an emergent problem of AML. Therefore, in any case with bilateral corneal herpes keratitis, the patient should be evaluated for immune system deficiency.Copyright: © 2023 Oman Ophthalmic Society.