狗类室内脑室肿瘤的放射治疗数据有限。本回顾性纵向研究（2011年9月至2018年）对11只患有室内肿块的狗进行了立体定向放射治疗（SRT）。6例病例中有手术或尸检获得的病理诊断结果，其中3例为脉络丛乳头状瘤，2例为癌，另有1例为脑室管瘤。其余被磁共振成像（MRI）诊断为疑似脉络丛瘤或脑室管瘤。肿瘤位于第三脑室或侧脑室（8例），第四脑室（2例）和小脑桥角（1例）。三只狗在接受放射治疗前进行了手术切除，并在治疗中出现明显的残余/复发疾病。狗接受了8 Gray × 3次（7例）或15 Gray × 1次（4例）的照射。十只狗在分析时已死亡，一只仍存活。从首次SRT治疗开始估计的中位总生存时间（OS）为16.9个月（515天，95％CI 33-1593天）。两例確诊病理学为癌症的狗的生存时间分别为24天和133天，而病理学为中度到重度室腔扩大的狗的生存时间为24到113天。总共有10/11个狗在主人或临床医师的观察下显示临床症状改善，但有两例获益短暂，并在SRT后的6周内被安乐死。由于数据集小和随访成像有限，对放射相关并发症的结论有限。本研究提供了初步证据，显示了室内脑室肿瘤的放射治疗结果具有变异性，并且注意到了一些长期存活的病例。© 2023 The Authors. Veterinary and Comparative Oncology published by John Wiley & Sons Ltd.

Published radiotherapy data for canine intraventricular tumours are limited. In this retrospective, longitudinal study (9/2011-2018), 11 dogs with intraventricular masses were treated with stereotactic radiotherapy (SRT). Pathologic diagnosis was available from surgery or necropsy in 6/11 cases, revealing choroid plexus papilloma (3) or carcinoma (2), and ependymoma (1). The remainder were magnetic resonance imaging (MRI)-diagnosed as suspected choroid tumours or ependymomas. Tumours were located in the third or lateral ventricle (8), fourth ventricle (2), and cerebellopontine angle (1). Surgery was performed in three dogs prior to radiotherapy, and all showed gross residual/recurrent disease at treatment. Dogs received 8 Gray × 3 fractions (7), or 15 Gray × 1 fraction (4). Ten dogs were deceased at analysis, and one was living. The estimated median overall survival time (OS) from first SRT treatment was 16.9 months (515 days, 95% CI 33-1593 days). The survival time for two pathology-diagnosed carcinoma dogs were 24 and 133 days, respectively, and survival time for dogs with moderate to marked ventriculomegaly (4/11) ranged from 24 to 113 days. A total of 10/11 showed clinical improvement per owner or clinician, but two had short-lived benefits and were euthanized within 6 weeks of SRT. Limited conclusions on radiation-specific complications are possible due to the small dataset and limited follow-up imaging. This study provides preliminary evidence that radiotherapy outcomes are variable with intraventricular tumours, and some long-term survivors are noted.© 2023 The Authors. Veterinary and Comparative Oncology published by John Wiley & Sons Ltd.