通过定性系统性回顾，研究儿童对化疗引起的认知损害——俗称"chemobrain"（化疗脑）的经历以及其对儿童社交、学术和日常生活技能的影响。儿童在大脑仍在发育阶段接受化疗可能对幸存者的终身生活造成长期不利影响。目前对他们的生活经历了解还存在显著的空白，包括儿童在治疗后面临的自我认知障碍。只有通过对定性研究文献的探索，听取儿童本人和/或父母代理人的发言，才能充分填补这一空白。 我们进行了MEDLINE、Embase、PsycINFO和CINAHL数据库的搜索。包含标准为定性研究，重点关注儿童（0-18岁）在化疗期间和/或之后的阶段，探讨儿童对chemobrain的经历。从6项研究中总结出了两个发现。(1)Chemobrain会对学术和心理社交产生影响，这一影响可能被教育提供者所忽视。(2)儿童及其父母对回归学校、社交生活以及作为独立社会成员的未来有所顾虑。儿童的经历主要与他们学术和社交功能的变化有关。 本综述强调了两个重要的考虑因素：(1)幼儿期癌症幸存者的生活经历指导未来应该瞄准哪些干预措施；(2)需要在这个领域进行更多的定性研究，并改善现有文献的质量报告，因为这是当前领域的一个空白。© 2023. 对于本文作者。

To examine children's experiences of chemotherapy-induced cognitive impairment--colloquially "chemobrain"--and the impact on children's social, academic, and daily living skills via a qualitative systematic review. Experiencing chemotherapy as a child, when the brain is still developing, may cause lifelong detriment to survivors' lives. There is a significant gap in understanding their lived experience, including the self-identified barriers that children face following treatment. Such a gap can only be fully bridged by listening to the child's own voice and/or parent proxy report through an exploration of the qualitative research literature.A search of MEDLINE, Embase, PsycINFO, and CINAHL databases was conducted. Inclusion criteria were qualitative studies with a focus on children (0-18 years) during and/or following chemotherapy treatment and explored children's experiences of chemobrain.Two synthesized findings were identified from six studies. (1) Chemobrain has an academic and psychosocial impact, which may not be understood by education providers. (2) Children and their parents have concerns about their reintegration and adaptation to school, social lives, and their future selves as independent members of society. Children's experiences primarily related to changes in their academic and social functioning.This review highlights two important considerations: (1) the lived experiences of pediatric childhood cancer survivors guiding where future interventions should be targeted, and (2) a need to perform more qualitative research studies in this area, as well as to improve the quality of reporting among the existing literature, given that this is a current gap in the field.© 2023. The Author(s).