三项研究报告了颞叶切除术后的三叉神经感觉减退症。然而，尚未报告过激光间接热疗（LITT）后感觉减退症的病例。我们报告了一例58岁男性患者，患有难治性癫痫，因左海马旁回多结节空泡状神经元瘤行活检和MRI引导下的LITT，术后立即出现左V3分布的感觉减退症状，包括口腔内和耳内。在6个月的随访中，感觉减退症状仍然存在但有所改善，并且患者不再发作。虽然小脑桥角和桥前水池被认为是热绝缘体，但我们推测热损伤是通过这些空间传导到三叉神经的池段或Meckel洞的下V3支。此外，MRI热成像骨骼破坏在颅骨基部产生一个盲区，影响了消融的实时可视化。© 2023 S. Karger AG, Basel.

Three studies have reported trigeminal hypesthesia following temporal lobe resection. However, no cases of hypesthesia have been reported following laser interstitial thermal therapy (LITT). We report the first case of trigeminal hypesthesia as a complication of otherwise successful LITT in a patient with drug-resistant epilepsy. A 58-year-old male with drug-resistant epilepsy secondary to a left parahippocampal gyrus multinodular and vacuolating neuronal tumor underwent biopsy and MRI-guided LITT. Immediately postoperatively, the patient reported hypesthesia in the left V3 distribution, including inside the mouth and ear. At 6-month follow-up, hypesthesia was present but improving, and the patient was seizure-free. While the cerebellopontine angle and prepontine cisterns are considered thermal insulators, we hypothesize that thermal injury was conducted through these spaces to the cisternal segment of the trigeminal nerve or to the inferior V3 branch in Meckel's cave. Moreover, real-time visualization of the ablation is impacted by a blind spot at the skull base, created from bone disruption of MRI thermography.© 2023 S. Karger AG, Basel.