本研究旨在比较脊髓刺激（SCS）和血管内再血管化治疗糖尿病足溃疡的效果。回顾性分析符合纳入标准的104例患有糖尿病足溃疡的患者，按照治疗方式分为SCS治疗组（n = 46）和血管内再血管化治疗组（n = 46）。分别在术前和术后六个月时，分析患者的生活质量评分（患者肝癌生活质量量表v2.0）、视觉疼痛模拟评分、下肢皮肤温度、下肢动脉超声结果和下肢肌电图结果，比较两种治疗方法对糖尿病足溃疡的疗效。共有92例患者（男性：73.9%，平均年龄：66.51 ± 11.67岁）完成了术后六个月的随访。术后六个月时，SCS治疗组的生活质量评分（25.54% vs 13.77%，p < 0.05），疼痛评分减少幅度（69.18% vs 37.21%，p < 0.05）和足部温度减少幅度（18.56% vs 7.24%，p < 0.05）均明显高于血管内再血管化治疗组。彩色多普勒血管超声检查中下肢血管扩张程度和神经传导速度在术后六个月时SCS治疗组均明显高于血管内再血管化治疗组（p < 0.05）。术后六个月时，SCS治疗较血管内再血管化治疗在改善生活质量、缓解疼痛、改善下肢皮肤温度、增加下肢血流和改善神经传导方面表现出更好的疗效。版权所有 © 2023 The Authors. Elsevier Inc.保留所有权利。

We aimed to compare the effects of spinal cord stimulation (SCS) with those of endovascular revascularization on the treatment of diabetic foot ulcers.A total of 104 patients with diabetic foot ulcers who met the inclusion criteria were retrospectively analyzed and classified to the SCS treatment group (n = 46) and endovascular revascularization treatment group (n = 46). The quality-of-life scores (Quality of Life Scale for Patients with Liver Cancer v2.0), visual pain analog scale score, lower limb skin temperature, lower limb arterial ultrasound results, and lower extremity electromyography results were analyzed to compare the efficacy of the two treatments for diabetic foot ulcers in the two groups before surgery and six months after surgery.A total of 92 patients (men: 73.9%, mean age: 66.51 ± 11.67 years) completed the six-month postoperative follow-up period. The patients in the SCS treatment group had a higher quality-of-life score (25.54% vs 13.77%, p < 0.05), a larger reduction in pain scores (69.18% vs 37.21%, p < 0.05), and a larger reduction in foot temperature (18.56% vs 7.24%, p < 0.05) than those of the endovascular revascularization treatment group at six months after surgery. The degree of vasodilation in the lower limbs on color Doppler arterial ultrasound and the nerve conduction velocity were higher in the SCS treatment group than in the endovascular revascularization treatment group at six months after surgery (p < 0.05).SCS was more effective than endovascular revascularization in improving quality of life, relieving pain, improving lower limb skin temperature, increasing lower limb blood flow, and improving nerve conduction in patients with diabetic foot ulcers at six months after surgery.Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.