造血干细胞移植研究中的多重结果、多个变量及变量选择分析。
The analysis of multiple outcomes, multiple variables and variables selection in hematopoietic cell transplantation studies.
发表日期:2023 Sep
作者:
Soyoung Kim, Xi Fang, Kwang Woo Ahn
来源:
Best Pract Res Cl Ob
摘要:
在癌症研究中,如白血病的造血干细胞移植(HCT)等,研究时间至事件数据是常见的。对于单变量生存结果,即一种事件类型,已经进行了大量工作。然而,在实践中,一个受试者通常会接受多种类型的结果。在本文中,我们回顾了包括竞争风险数据、复发事件数据和复合终点在内的多种类型的右删失数据。我们还提供了造血干细胞移植数据的例子。版权所有© 2023 Elsevier Ltd. 保留所有权利。
It is common to study time-to-event data in cancer research such as hematopoietic cell transplantation (HCT) for leukemia. The extensive work has been done for the univariate survival outcome, that is, one event type. However, in practice a subject is often exposed to multiple types of outcomes. In this article, we review various types of right-censored data with multiple outcome types including competing risks data, recurrent event data, and composite endpoints. We also provide hematopoietic cell transplantation data examples.Copyright © 2023 Elsevier Ltd. All rights reserved.