放射性肝损伤中18F-FAPI摄取增加。
Increased 18F-FAPI Uptake in Radiation-Induced Liver Injury.
发表日期：2023 Oct 01
作者：
Jing Zhang, Shuqin Jiang, Rusen Zhang, Linqi Zhang
来源：
CLINICAL NUCLEAR MEDICINE
摘要：
一名51岁的患有乳腺癌的妇女在大约3个月前进行了全面的手术切除和化学放疗。随后进行的腹部超声检查发现肝脏的IV/VIII节段出现了新的回声减低的病灶。18F-FDG PET/CT显示肝脏病灶未出现异常摄取。随后，患者被纳入18F-FAPI PET/CT临床试验，以评估肝脏病灶。强烈的18F-FAPI活性被确定在肝脏病灶中。最后，病理学分析结合影像随访证实了放射性肝损伤的诊断。Copyright © 2023 Wolters Kluwer Health，Inc. 保留所有权利。
A 51-year-old woman with breast cancer underwent a complete surgical resection and chemoradiotherapy approximately 3 months ago. Follow-up abdominal ultrasound detected a new lesion with decreased echogenicity in the hepatic segment IV/VIII. 18F-FDG PET/CT showed the hepatic lesion without abnormal uptake. The patient was subsequently enrolled in a clinical trial of 18F-FAPI PET/CT to assess the hepatic lesion. An intense 18F-FAPI activity was identified in the hepatic lesion. Finally, pathological analysis combined with imaging follow-up confirmed the diagnosis of radiation-induced liver injury.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.