一个非规范的作用:Hippo通路调节因子MAP4K2在能量应激时控制自噬和细胞存活。
A non-canonical role: The Hippo pathway regulator MAP4K2 controls autophagy and cell survival upon energy stress.
发表日期:2023 Sep 07
作者:
Anne Schreiber
来源:
MOLECULAR CELL
摘要:
在本期中,Seo等人报告了Hippo激酶MAP4K2在能量应激反应中通过调节自噬和细胞存活发挥了非规范的功能,这与头颈癌治疗的相关性和治疗潜力有关。版权所有© 2023 Elsevier Inc. 保留所有权利。
In this issue, Seo et al.1 report a non-canonical function of the Hippo kinase MAP4K2 in energy stress response by regulating autophagy and cell survival, with relevance and therapeutic potential for head and neck cancer treatment.Copyright © 2023 Elsevier Inc. All rights reserved.