台灣黑色素瘤診斷與管理臨床實踐共識。
Clinical practice consensus for the diagnosis and management of melanoma in Taiwan.
发表日期：2023 Sep 08
作者：
Chiao-En Wu, Yi-Hua Liao, Cheng-Lin Wu, Ruoh-Fang Yen, Chia-Chi Lin, Muh-Hwa Yang, Chueh-Chuan Yen, Wu-Chou Su, Chia-Jui Yen, Yi-Fang Chang, Ming-Fang Wu, Youngsen Yang, Chen-Yuan Lin, Wen-Chi Yang, Hui-Ching Wang, Cheng-Yuan Li, Yin-Yu Ho, Yao-Yu Chang, Chieh-Shan Wu, Hsiu-Cheng Hsu, Kuang-Hua Chen, Yenlin Huang, Chih-Jung Chen, Pei-Ju Chuang, Yung-Chi Lai, Yu-Yi Huang, Neng-Chuan Tseng, Yi-Ting Huang, Chia-Yu Chu, John Wen-Cheng Chang
来源：
Stem Cell Research & Therapy
摘要：
台湾罕见黑色素瘤。亚洲黑色素瘤与西方黑色素瘤不同，因为肢端和黏膜黑色素瘤占了大多数黑色素瘤病例，导致肿瘤行为和基因特征不同。考虑到西方国家的临床指南，台湾的专家们制定了本地临床实践共识指南。该共识包括诊断、分期和手术和全身治疗，仅基于台湾专家评估的临床证据、当地流行病学数据和可用资源。该共识强调外科治疗的重要性，尤其是对哨兵淋巴结活检。此外，患者在全身治疗前必须进行BRAF的分子检测。此外，免疫治疗和靶向治疗被优先考虑为全身治疗。该共识旨在帮助台湾的临床医生根据可用证据进行患者的诊断和治疗。版权所有 © 2023。Elsevier B.V. 发表。
Melanoma is rare in Taiwan. Asian melanoma is distinct from Western melanoma because acral and mucosal melanoma accounts for the majority of melanoma cases, leading to distinct tumor behaviors and genetic profiling. With consideration of the clinical guidelines in Western countries, Taiwanese experts developed a local clinical practice consensus guideline. This consensus includes diagnosis, staging, and surgical and systemic treatment, based only on clinical evidence, local epidemiology, and available resources evaluated by experts in Taiwan. This consensus emphasizes the importance of surgical management, particularly for sentinel lymph node biopsies. In addition, molecular testing for BRAF is mandatory for patients before systemic treatment. Furthermore, immunotherapy and targeted therapy are prioritized for systemic treatment. This consensus aimed to assist clinicians in Taiwan in diagnosing and treating patients according to available evidence.Copyright © 2023. Published by Elsevier B.V.