研究动态
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揭示对急性放射性皮炎的管理:来自MASCC肿瘤皮肤病学研究组的洞察力。

Shedding light on the management of acute radiation dermatitis: insight from the MASCC Oncodermatology study group.

发表日期:2023 Sep 11
作者: Pierluigi Bonomo, Julie Ryan Wolf
来源: Best Pract Res Cl Ob

摘要:

本文重点介绍了一系列有关急性放射性皮炎的预防和治疗的近期发表研究稿件。这些荟萃分析为多国癌症支持护理协会(MASCC)肿瘤皮肤学研究组更新的临床实践指南提供了额外的证据,用于急性放射性皮炎的预防和治疗。这些文集阐明了关于急性放射性皮炎的当前可用证据,突出了已有知识、有效治疗方法以及未来临床试验的拟议领域。总体而言,在从1946年至2023年1月对文献进行初步系统回顾的基础上,共检索并纳入了51个随机对照试验,进行了定量分析。有关各种治疗干预的临床影响的讨论包括:使用止汗剂和除臭剂、屏障膜和敷料、天然和其他剂、光生物调节治疗、局部皮质类固醇、局部非类固醇类剂、皮肤卫生和洗涤,以及StrataXRT和乳腺癌患者中的Mepitel膜。荟萃分析的全面性及其相关发现有助于减少急性放射性皮炎治疗中的不一致性,并促进全球临床实践中采用的治疗干预的一致性。© 2023. 作者(们),根据Springer Nature下的德国Springer-Verlag GmbH独家许可。
This paper highlights a collection of eleven recently published manuscripts on the prevention and management of acute radiation dermatitis. These meta-analyses provide additional evidence for the updated clinical practice guidelines by the Multinational Association of Supportive Care in Cancer (MASCC) Oncodermatology study group for prevention and management of acute radiation dermatitis. The collection of papers elucidate the currently available evidence on acute radiation dermatitis, highlighting consolidated knowledge, effective treatments, and proposed areas for future clinical trials. Overall, a total of 51 randomized controlled trials were retrieved and included for quantitative analysis of an initial systematic review of literature from 1946 to January 2023. Discussion of the clinical impact of various therapeutic interventions include: antiperspirant and deodorant use, barrier films and dressings, natural and miscellaneous agents, photobiomodulation therapy, topical corticosteroids, topical non-steroidal agents, skin hygiene and washing, as well as StrataXRT and Mepitel film in breast cancer patients. The comprehensive nature of the meta-analyses and their related findings may help reduce the discrepancies in in treatment of acute radiation dermatitis and facilitate consistency of therapeutic interventions employed in clinical practice worldwide.© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.