本文综述了关于槲皮素（quercetin）的可获得性、代谢、对生理过程和疾病的影响的当前信息，重点关注槲皮素在调节雌性生殖过程、预防和治疗哺乳动物雌性生殖障碍方面的效应、作用机制和可能的应用领域。现有信息表明，槲皮素及其类似物能够抑制增殖、促进凋亡、激活再生过程、治疗免疫、炎症、心血管、神经退行性、胃和代谢紊乱以及癌症，抑制微生物，保护骨骼和肝脏，缓解疼痛，改善肉体和精神表现，延长寿命。槲皮素对哺乳动物雌性生殖过程的正面影响经过了充分的文献证实。它能促进卵巢卵泡和卵母细胞发育，提高卵子和胚胎的质量，增加不同物种的繁殖能力。这些效应可能通过改变垂体和卵巢激素、生长因子和细胞因子以及它们的受体和后受体信号传导途径来介导。由于这些效应，槲皮素可以作为生殖生物刺激剂，在预防、缓解和治疗多种雌性生殖障碍方面具有应用潜力，并能增加雌性生殖系统对化疗、温度应激和环境污染物的不良影响的抵抗力。

This paper reviews the current information concerning availability, metabolism of quercetin, its effects on physiological processes and illnesses with focus on the effects, mechanisms of action and areas of possible application of quercetin in control of female reproductive processes, prevention and treatment of their disorders in mammals.The available information demonstrated the ability of quercetin and its analogues to inhibit proliferation and to promote apoptosis, to activate regenerative processes, to treat immune, inflammatory, cardiovascular, neurodegenerative, gastric and metabolic disorders and cancer, to suppress microorganisms, to protect bones and liver, to relieve pain, to improve physical and mental performance, and to prolong life span.The positive influences of quercetin on mammalian female reproductive processes are well documented. It can promote ovarian follicullo- and oogenesis, improve quality of oocytes and embryos, increase fecundity in various species. These effects can be mediated by changes in pituitary and ovarian hormones, growth factors and cytokines, in their receptors and post-receptory signaling pathways. Due to these effect, quercetin can be applicable as biostimulator of reproduction, for prevention, mitigation and treatment of several female reproductive disorders, as well as to increase resistance of female reproductive system to adverse effect of chemotherapy, temperature stress and environmental contaminants.