N6-甲基腺苷（m6A）甲基化是一种动态可逆的表观遗传修饰过程。越来越多的研究认识到m6A修饰参与了泌尿系统肿瘤的发生、发展和进展。新兴研究探讨了m6A修饰在泌尿系统癌症中的作用。在本综述中，我们将总结m6A修饰与肾细胞癌、膀胱癌和前列腺癌之间的关系，并发现m6A调控因子在肿瘤细胞中的生物学功能。我们还将讨论可能的机制和未来应用前景，将其作为潜在的生物标志物或治疗靶点，造福泌尿系统癌症患者。©2023 Zeng等。

N6-methyladenosine (m6A) methylation is a dynamic and reversible procession of epigenetic modifications. It is increasingly recognized that m6A modification has been involved in the tumorigenesis, development, and progression of urological tumors. Emerging research explored the role of m6A modification in urological cancer. In this review, we will summarize the relationship between m6A modification, renal cell carcinoma, bladder cancer, and prostate cancer, and discover the biological function of m6A regulators in tumor cells. We will also discuss the possible mechanism and future application value used as a potential biomarker or therapeutic target to benefit patients with urological cancers.©2023 Zeng et al.