巨大的阳性非典型淋巴瘤激酶阳性非典型大细胞淋巴瘤病例报告。
A Giant Anaplastic Lymphoma Kinase Positive Anaplastic Large Cell Lymphoma: Case Report.
发表日期：2023 Sep 01
作者：
Xi Dai, Jing Ma, Cheng Ming, Yingqin Gao, Fan Lou, Tiesong Zhang, Qingjun He
来源：
Bone & Joint Journal
摘要：
Anaplastic lymphoma kinase-positive (ALK+) large cell lymphoma (ALCL)是一种全身性淋巴瘤。在儿童中，ALCL以ALK+为特征，侵袭头颈骨和皮肤的情况相对较少。我们报道了一例13岁男孩患有ALK+ ALCL的病例。他接受了取样活检手术。接着，该男孩接受了6个疗程的辅助化疗，使用了非霍奇金淋巴瘤-Berlin-Frankfurt-Münster (NHL-BFM)-90 K3方案。之后，他达到了部分缓解 (PR)。儿童发展ALCL是常见的，该病生长迅速。因此，对该患者进行了取样活检手术以及NHL-BFM-90 K3治疗是必要的。
Anaplastic lymphoma kinase-positive (ALK+) large cell lymphoma (ALCL) is a systemic lymphoma. The invasion of the head and neck bone and skin by ALK+ ALCL is relatively uncommon in children.We describe a 13-year-old boy diagnosed with ALK+ ALCL.He went a surgery of sampling biopsy procedure. Then the boy was treated with six cycles of adjuvant chemotherapy with Non-Hodgkin's Lymphoma-Berlin-Frankfurt-Munster (NHL-BFM)-90 K3 arm. Then, he achieved partial remission (PR).It is common for children to develop ALCL, which grows rapidly. Therefore, a sampling biopsy procedure and NHL-BFM-90 K3 were necessary for the patient.