延迟胃排空（DGE）是胰十二指肠切除术（PD）后常见的并发症。DGE会导致住院时间延长和生活质量下降。本研究分析了在PD后发展DGE的预测因素，同时排除外科并发症的情况下进行分析。收集了2010年1月至2018年6月30日瑞典国家胰腺癌登记处的数据，包括接受标准和保存幽门开放式PD的患者。数据分为两组，即无DGE组和有DGE组。将有DGE但无外科并发症的患者亚组与无DGE或任何其他外科并发症的患者进行比较。总共纳入了2503名患者，其中470名（19％）患有DGE。在DGE组中，238名同时存在其他外科并发症，而232名没有。术后胰漏（OR = 4.22，p <0.001），手术感染（OR = 1.44，p = 0.013），心脏疾病（OR = 1.32，p = 0.023）和医疗并发症（OR = 1.35，p = 0.025）增加了DGE的风险。与保留幽门切除术相比，标准PD（OR = 1.69，p = 0.001）以及胰十二指肠吻合术与胰胃吻合术相比（OR = 1.83，p <0.001）增加了风险。对于没有外科并发症的患者，标准PD和胰十二指肠吻合术仍增加了DGE的风险。在这个全国队列中，与保存幽门PD相比，标准PD后DGE更为常见，并且与胰胃吻合术相比，胰十二指肠吻合术重建亦增加了DGE的风险。© 2023. 作者。

Delayed gastric emptying (DGE) is a common complication after pancreatoduodenectomy (PD). DGE causes prolonged hospital stay and a decrease in quality of life. This study analyzes predictive factors for development of DGE after PD, also in the absence of surgical complications.Data from the Swedish National Pancreatic Cancer Registry for patients undergoing standard and pylorus preserving open PD from January 2010 until June 30, 2018, were collected. Data were analyzed in two groups, no DGE and DGE. A subgroup of patients with DGE but without surgical complications was compared to patients without DGE or any other surgical complication.In total, 2503 patients were included, of which 470 (19%) had DGE. In the DGE group, 238 had other coexisting surgical complications and 232 had not. Postoperative pancreatic fistula (OR = 4.22, p < 0.001), surgical infection (OR = 1.44, p = 0.013), heart disease (OR = 1.32, p = 0.023) and medical complications (OR = 1.35, p = 0.025) increased the risk for DGE. A standard PD compared with pylorus preserving resection (OR = 1.69, p = 0.001) and a reconstruction with a pancreaticojejunostomy compared with a pancreaticogastrostomy (OR = 1.83, p < 0.001) increased the risk. For patients without surgical complications, a standard PD and reconstruction with pancreaticojejunostomy still increased the risk for DGE.DGE is more common after standard PD compared to pylorus preserving PD and after reconstruction with PJ compared to PG in this national cohort, both in the presence of other surgical complications as well as in the absence of other complications.© 2023. The Author(s).