研究动态
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胃转移的两例乳腺癌病例。

Two Cases of Breast Cancer With Gastric Metastasis.

发表日期:2023 Aug
作者: Akane Ito, Masaki Nakatsubo, Ryusei Yoshino, Nana Yoshida, Masahiro Kitada
来源: Bone & Joint Journal

摘要:

难以与原发性胃癌区分开胃转移乳腺癌。本文报告了两例转移至胃癌的乳腺癌病例,并对相关文献进行了综述。第一例,一名77岁女性在上消化道内窥镜检查后被诊断为腺癌,并显示胃体部位有糜烂病变。她接受了芳香化酶抑制剂和CDK4 / 6抑制剂的治疗,但五年后出现了多发性骨转移和胃病变,目前正在接受每周紫杉醇(PTX)和bev治疗。第二例,一名63岁女性行全乳房切除术和腋窝淋巴结清扫(浸润性小叶癌)。手术后11年,患者出现咽部紧迫感,并经上消化道内窥镜检查发现胃体和胃后壁的4型胃肿瘤。总之,对于乳腺癌的ILC或晚期乳腺癌患者出现胃症状和贫血时,根据可能的胃转移存在进行检查和治疗是非常重要的。版权所有 © 2023, Ito等。
Gastric metastases from breast cancer are difficult to distinguish from primary gastric cancer. We report two cases of gastric metastasis of breast cancer with a review of the literature. In the first case, a 77-year-old woman was diagnosed with adenocarcinoma after upper gastrointestinal endoscopy, which revealed an erosive lesion in the gastric corpus. She was treated with an aromatase inhibitor and a CDK4/6 inhibitor, but five years later, she developed multiple bone metastases and gastric lesions, and she is currently receiving weekly paclitaxel (PTX) and bev. In the second case, a 63-year-old woman underwent total mastectomy and axillary lymphadenectomy [invasive lobular carcinoma (ILC)]. Eleven years after the surgery, the patient complained of pharyngeal tightness, and upper gastrointestinal endoscopy revealed a type 4 gastric tumor in the gastric body and posterior wall. In conclusion, when a patient with ILC or advanced breast cancer presents with gastric symptoms and anemia, it is important to examine and treat the patient based on the possibility of gastric metastasis.Copyright © 2023, Ito et al.