颌骨放射性坏死（ORN）是头颈放疗的一种罕见但严重的迟发并发症。下颌骨的近邻原发肿瘤、放射剂量、口腔卫生状况差以及吸烟史是ORN的危险因素。ORN表现为开放性颌骨慢性感染，通常在放疗后的前3年发生；然而，接受头颈放疗的患者发展ORN的风险可能是无限的。手术在ORN病例的处理中起着重要作用，包括切除坏死骨块、清创和广泛切除术与重建手术。版权所有 © 2023 Elsevier Inc. 保留所有权利。

Osteoradionecrosis (ORN) is a rare but serious late complication of head and neck radiation therapy. The mandible, proximity of the primary tumor to the jawbones, radiation dose, poor oral hygiene, and smoking history are risk factors of ORN. ORN manifests as a chronic infection with exposed jawbone, which typically occurs in the first 3 years after radiotherapy; however, the risk for ORN development occurring in the patients who have undergone head and neck radiation therapy may be indefinite. Surgery has an important role in the management of cases of ORN, ranging from sequestrectomy, debridement, and extensive extirpative procedures with reconstructive surgery.Copyright © 2023 Elsevier Inc. All rights reserved.