肾细胞癌（RCC）是死亡率最高的十大恶性肿瘤之一。它表现出明显的异质性和强大的转移行为。肾细胞癌患者可能在不同的解剖部位出现单发性或多发性转移病灶，其预后取决于转移部位。在为患者考虑最佳治疗方法时，必须彻底评估重要的风险因素，例如完全切除的可行性、寡转移的存在以及患者的功能和身体状况。认识到肾细胞癌转移到不同器官的细微差别，有利于考虑旨在优化生存结果的潜在治疗方式。此外，识别转移部位有望增强转移性肾细胞癌患者的风险分层。本综述总结了有关不同 RCC 转移部位现状的最新数据，并阐明了它们在为 RCC 不同转移部位的临床管理策略提供信息方面的作用。版权所有 © 2024 作者。由 Wolters Kluwer Health, Inc. 出版

Renal cell carcinoma (RCC) stands among the top 10 malignant neoplasms with the highest fatality rates. It exhibits pronounced heterogeneity and robust metastatic behavior. Patients with RCC may present with solitary or multiple metastatic lesions at various anatomical sites, and their prognoses are contingent upon the site of metastasis. When deliberating the optimal therapeutic approach for a patient, thorough evaluation of significant risk factors such as the feasibility of complete resection, the presence of oligometastases, and the patient's functional and physical condition is imperative. Recognizing the nuanced differences in RCC metastasis to distinct organs proves advantageous in contemplating potential treatment modalities aimed at optimizing survival outcomes. Moreover, discerning the metastatic site holds promise for enhancing risk stratification in individuals with metastatic RCC. This review summarizes the recent data pertaining to the current status of different RCC metastatic sites and elucidates their role in informing clinical management strategies across diverse metastatic locales of RCC.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.