人们越来越意识到临床试验和临床实践中要测量的结果的循证选择。目前，心脏肿瘤学没有核心结果集（COS），这可能会阻碍研究有效性和心脏肿瘤护理质量的（国际）国家比较。本研究的目的是制定一个标准且务实的以患者为中心的结果集，以评估和监测有心血管疾病风险或患有心血管疾病的癌症患者和幸存者。通过审查登记和指南生成了一份结果领域列表，以及六个患者访谈。在开始 2022 年 1 月至 6 月期间进行的两轮 Delphi 程序之前，项目团队审查并完善了结果领域。小组成员（包括医疗保健提供者和研究人员）受邀对结果的重要性进行评级。来自 11 个国家的 26 名专家对 93 项结果（第一轮）和 63 项结果（第二轮）的清单进行了评级，以就一系列结果指标以及人口因素、健康状况和治疗变量达成共识。最终的 COS 包括 15 个结果指标，反映四个核心领域：生活影响 (n = 2)、病理生理表现 (n = 9)、资源利用/经济影响 (n = 1) 和死亡率/生存 (n = 3)。接下来，包括 6 个人口统计因素、21 个健康状况、3 个心血管因素和 9 个癌症变量。这是国际上第一个针对心脏肿瘤学开发的 COS。该套件旨在促进心脏肿瘤护理的（国际）国家比较，使用标准化参数和有意义的以患者为中心的结果进行研究和护理质量评估。© 作者 2024。由牛津大学出版社代表欧洲心脏病学会。

There is an increasing awareness of the evidence-based selection of outcomes to be measured in clinical trials and clinical practice. Currently, there is no core outcome set (COS) for cardio-oncology, which may hinder the (inter)national comparison of the effectiveness of research and the quality of cardio-oncology care. The aim of this study is to develop a standard and pragmatic patient-centred outcome set to assess and monitor cancer patients and survivors at risk of or with cardiovascular diseases.A list of outcome domains was generated through a review of registries and guidelines, and six patient interviews. The project team reviewed and refined the outcome domains prior to starting a two-round Delphi procedure conducted between January-June 2022. The panellists, including healthcare providers and researchers, were invited to rate the importance of the outcomes. 26 experts from 11 countries rated a list of 93 outcomes (round 1) and 63 outcomes (round 2) to gain consensus on a list of outcome measures, and of demographic factors, health status and treatment variables. The final COS includes 15 outcome measures, reflecting four core areas: life impact (n = 2), pathophysiological manifestations (n = 9), resource use/economic impact (n = 1), and mortality/survival (n = 3). Next, six demographic factors, 21 health status, three cardiovascular and nine cancer variables were included.This is the first international development of a COS for cardio-oncology. This set aims to facilitate (inter)national comparison in cardio-oncology care, using standardised parameters and meaningful patient-centred outcomes for research and quality of care assessments.© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology.