研究动态
Articles below are published ahead of final publication in an issue. Please cite articles in the following format: authors, (year), title, journal, DOI.

乳腺癌手术后头皮转移:病例报告。

Scalp Metastasis After Breast Cancer Surgery: A Case Report.

发表日期:2024
作者: Jingxuan Wu, Wenzhu Zhang, Hong Zhang, Xingjia Lu, Biqing Luan, Qizhi Yang, Liang Chen, Wenlin Chen, Fei Ge
来源: Bone & Joint Journal

摘要:

乳腺癌是影响全世界女性的最常见恶性肿瘤之一。乳腺癌是一种复杂的疾病,其特征是乳腺组织中细胞的异常生长。转移,即癌细胞从原发肿瘤部位扩散到远处器官,是乳腺癌治疗的主要挑战。虽然远处转移是乳腺癌的一个众所周知的特征,但头皮受累相对较少。头皮转移的发生意味着疾病已经发展到晚期。这位 51 岁的女性发现她的右乳房有一个坚硬、无痛的肿块,该肿块已经存在两年了。刺痛了一个月,活检显示肿块是右乳浸润性癌。影像学检查提示肿瘤为恶性。乳腺癌改良根治术后进行辅助内分泌治疗和术后辅助化疗。 11个月后,采用放射治疗并替代内分泌治疗。手术后32个月,发现头皮肿瘤;病理活检证实了乳腺癌的起源;三个月后,发现骨、脑、内脏转移。随后,她接受口服卡培他滨治疗,并入院进行高级抢救治疗。目前处于疾病稳定状态,病情得到有效控制,未发现新的转移病灶。© 2024 Wu et al.
Breast cancer is one of the most common malignant tumors affecting women worldwide. Breast cancer is a complex disease characterized by abnormal growth of cells in the breast tissue. Metastasis, the spread of cancer cells from the primary tumor site to distant organs, is a major challenge in the management of breast cancer. Although metastasis to distant sites is a well-known feature of breast cancer, scalp involvement is relatively rare. The occurrence of scalp metastasis signifies an advanced stage of the disease. The 51-year-old female discovered a firm, painless mass in her right breast that had been there for two years. It had been pricking for a month, and the biopsy revealed that the mass was invasive carcinoma of the right breast. Imaging tests suggested that the tumor was malignant. Adjuvant endocrine therapy and postoperative adjuvant chemotherapy were administered following a modified radical resection for breast cancer. Eleven months later, radiation treatment and replace endocrine therapy was used. 32 months following surgery, a scalp tumor was discovered; a pathology biopsy verified the origin of the breast cancer; three months later, bone, brain, and visceral metastases were discovered. After that, she received oral capecitabine treatment and was admitted into the hospital for advanced rescue treatment. She is currently in the disease stability state, her disease is effectively managed, and no new metastatic lesions have been discovered.© 2024 Wu et al.