研究动态
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痣样基底细胞癌综合征的 18F-FDG PET/CT 结果:系统评价和新病例报告。

18F-FDG PET/CT findings in nevoid basal cell carcinoma syndrome: a systematic review and a new case report.

发表日期:2024 May 28
作者: Jing Zhang, Yonghong Zhang, Yumeng Jiang, Aodi Xu, Yanli Wang
来源: Bone & Joint Journal

摘要:

为了展示和分析这种罕见痣样基底细胞癌综合征 (NBCCS) 的 18F-FDG 正电子发射断层扫描/计算机断层扫描 (PET/CT) 结果。一名患有左侧浸润性乳腺癌的 71 岁女性接受激素治疗治疗6个月,并进行18F-FDG PET/CT检查进行疗效评估。 18F-FDG PET/CT显示治疗后的改善和其他意想不到的发现,包括皮肤上多发18F-FDG摄取结节、双侧肋骨囊性病变骨质扩张、异位钙化和右侧输尿管扩张。她没有已知的家族史。随后,患者接受手术切除所有皮肤结节,术后病理为多发性基底细胞癌。最终做出NBCCS的综合诊断。该患者仍在随访中。此外,我们还从文献中总结了 18F-FDG PET/CT 报告的病例 (n = 3)。由于不同的诊断和治疗结果,在 18F-FDG PET/CT 上认识这种综合征非常重要。© 2024。作者。
To demonstrate and analyze the 18F-FDG positron emission tomography/computed tomography (PET/CT) findings in this rare nevoid basal cell carcinoma syndrome (NBCCS).A 71-year-old woman with the left invasive breast cancer was treated with hormone therapy for six months and underwent the 18F-FDG PET/CT examination for efficacy evaluation. 18F-FDG PET/CT revealed the improvement after treatment and other unexpected findings, including multiple nodules on the skin with 18F-FDG uptake, bone expansion of cystic lesions in the bilateral ribs, ectopic calcifications and dilated right ureter. She had no known family history. Then, the patient underwent surgical excision of the all skin nodules and the postoperative pathology were multiple basal cell carcinomas. Finally, the comprehensive diagnosis of NBCCS was made. The patient was still in follow-up. Additionally, we have summarized the reported cases (n = 3) with 18F-FDG PET/CT from the literature.It is important to recognize this syndrome on 18F-FDG PET/CT because of different diagnoses and therapeutic consequences.© 2024. The Author(s).