2024 年，世界卫生组织 (WHO) 推出了新的淋巴肿瘤分类，这是对之前使用的分类第四版修订版 (WHO-4R) 的修订。然而，这意味着现在有两个分类同时使用：世界卫生组织分类第五版（WHO-5）和国际共识分类（ICC）。本次审查没有像其他地方所描述的那样对每种疾病实体进行全面审查，而是重点关注 WHO-5 和 ICC 对 WHO-4R 所做的修订以及它们之间关于 B 细胞肿瘤的差异。相似之处包括皮肤边缘区淋巴瘤、冷凝集素病、非原发性渗出性淋巴瘤型渗出性淋巴瘤和灰区淋巴瘤。差异包括浆细胞肿瘤、高级别 B 细胞淋巴瘤（双重打击淋巴瘤）、滤泡性淋巴瘤、免疫缺陷和失调的 LPD、结外大 B 细胞淋巴瘤、惰性 B 细胞淋巴瘤转化和弥漫性大 B 细胞淋巴瘤淋巴瘤，未另有说明。了解两种最新分类之间的异同将有助于淋巴肿瘤的日常诊断实践和未来研究。© 2024。日本血液学会。

In 2024, the World Health Organization (WHO) launched a new classification of lymphoid neoplasms, a revision of the previously used Revised 4th Edition of their classification (WHO-4R). However, this means that two classifications are now in simultaneous use: the 5th Edition of the WHO classification (WHO-5) and the International Consensus Classification (ICC). Instead of a comprehensive review of each disease entity, as already described elsewhere, this review focuses on revisions made in both the WHO-5 and ICC from WHO-4R and discrepancies between them regarding B-cell neoplasms. Similarities include cutaneous marginal zone lymphoma, cold agglutinin disease, non-primary effusion lymphoma-type effusion-based lymphoma, and gray zone lymphoma. Differences include plasma cell neoplasms, high-grade B-cell lymphoma (double hit lymphoma), follicular lymphoma, LPD with immune deficiency and dysregulation, extranodal large B-cell lymphoma, transformations of indolent B-cell lymphomas, and diffuse large B-cell lymphoma, not otherwise specified. Understanding the similarities and differences between the two latest classifications will aid daily diagnostic practice and future research on lymphoid neoplasms.© 2024. Japanese Society of Hematology.