使用体外、体内和微流体模型对脑肿瘤进行建模：对当前发展的回顾。
Modeling of brain tumors using in vitro, in vivo, and microfluidic models: A review of the current developments.
发表日期：2024 May 30
作者：
Richu Raju R, Nour M AlSawaftah, Ghaleb A Husseini
来源：
Disease Models & Mechanisms
摘要：
尽管科学在癌症化疗和研究方面取得了许多进步，但脑癌是治疗最复杂的疾病之一。确定这种疾病的潜在治疗方法的主要障碍之一是难以模拟大脑和周围微环境的复杂性以了解潜在的治疗方法。本文讨论了一些旨在应对这些挑战的最重要的体外、体内和微流体脑肿瘤模型。© 2024 作者。
Brain cancers are some of the most complex diseases to treat, despite the numerous advances science has made in cancer chemotherapy and research. One of the key obstacles to identifying potential cures for this disease is the difficulty in emulating the complexity of the brain and the surrounding microenvironment to understand potential therapeutic approaches. This paper discusses some of the most important in vitro, in vivo, and microfluidic brain tumor models that aim to address these challenges.© 2024 The Author(s).