研究动态
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意外挑战:无风险健康患者回肠远端低分化转移性粘液腺癌引起明显小肠梗阻。

An Unexpected Challenge: Marked Small Bowel Obstruction Arising From a Poorly Differentiated Metastatic Mucinous Adenocarcinoma of the Distal Ileum in a Risk-Free Healthy Patient.

发表日期:2024 Jun
作者: Jennie An, Barbara Fontenelle, Riddhi Chaudhari, Rob Mulloy, Sofiane El Djouzi
来源: PHYSICAL THERAPY & REHABILITATION JOURNAL

摘要:

腺癌虽然是小肠癌中的主要变异,但它是更广泛的原发性小肠恶性肿瘤的一个组成部分,其发生率明显较低。由于其起病隐匿和腹部症状的非特异性,此类恶性肿瘤的诊断常常明显延迟。一名 69 岁的白人男性到急诊室就诊,表现为急性、剧烈、绞痛性腹痛,并伴有单次呕吐,所有症状均在一天内发生。他的病史以胃食管反流病 (GERD) 和局限性前列腺腺癌而闻名,并受到泌尿外科团队的严密监测。患者生活方式的特点是戒烟戒酒、坚持营养饮食以及定期进行体育活动。随后对计算机断层扫描 (CT) 上显示的异常肿块进行检查和手术切除,最终诊断为 IV 期低分化腺癌。我们报告此病例是为了激发有关小肠腺癌 (SBA) 早期诊断技术的研究。在该病例中,一名健康个体出现隐隐约约的腹痛和单次呕吐。诊断需要手术切除肿瘤,并观察到转移情况。由于 SBA 的罕见性,我们认为应该研究不同的诊断措施和辅助治疗,以便更早诊断并随后获得更好的患者结果。版权所有 © 2024,An 等人。
Adenocarcinoma, while constituting the predominant variant among small bowel cancers, is a component of the broader category of primary small bowel malignancies, which are notably infrequent in occurrence. The diagnosis of such malignancies is often markedly delayed, a consequence of their insidious onset and the nonspecific nature of the abdominal symptoms presented. A 69-year-old Caucasian male presented to the emergency department manifesting acute, sharp, and colicky abdominal pain accompanied by a single episode of vomiting, all developing over one day. His medical history was notable for gastroesophageal reflux disease (GERD) and regionally confined prostate adenocarcinoma, which was under meticulous surveillance by the urological team. The patient's lifestyle was characterized by abstention from alcohol and tobacco, adherence to a nutritious diet, and a commitment to regular physical activity. Subsequent examination and surgical excision of an abnormal mass, as delineated on computed tomography (CT), culminated in the diagnosis of a stage IV, poorly differentiated adenocarcinoma. We have reported this case to spark research regarding early diagnostic techniques for small bowel adenocarcinoma (SBA). In this case, a healthy individual presented with vague abdominal pain and a single episode of vomiting. Diagnosis required the surgical resection of the tumor, where metastasis was also visualized. Due to the rare nature of SBA, we believe different diagnostic measures and adjuvant therapy should be researched for earlier diagnosis and subsequently better patient outcomes.Copyright © 2024, An et al.