噬血细胞性淋巴组织细胞增多症 (HLH) 是一种致命的紧急情况。诊断和治疗的延误不利于患者的健康。 HLH 的典型临床表现包括发热、血细胞减少、肝功能障碍、中枢神经系统受累和凝血功能障碍。我们报告了 7 例成人继发性 HLH 病例，该病例是通过我们中心总共 1200 例骨髓穿刺和环钻活检 (BMAT) 检查确诊的。具有各种表现和潜在触发因素，包括感染、恶性肿瘤和自身免疫性疾病。HLH 可能会出现非特异性体征和症状。早期识别 HLH 对于尽早开始治疗、预防多器官死亡至关重要失败。版权所有 © 2024，Khaw 等人。

Hemophagocytic lymphohistiocytosis (HLH) is a lethal emergency. Delays in diagnosis and treatment are detrimental to the health of patients. Classical clinical manifestations of HLH include fever, cytopenia, liver dysfunction, central nervous system involvement, and coagulopathy.We report seven cases of secondary HLH in adults diagnosed from a total of 1200 bone marrow aspiration and trephine biopsy (BMAT) examinations in our center, with various presentations and underlying triggers including infection, malignancy, and autoimmune disease.HLH can present with non-specific signs and symptoms.Early recognition of HLH is crucial to enable the commencement of therapy as early as possible to prevent mortality resulting from multi-organ failure.Copyright © 2024, Khaw et al.