起源于肝外胆管树中部的可切除胆管癌（CCA）历来被分类为肝门周围或远端CCA，具体取决于预期或实施的手术，分别是相关的肝切除术或胰十二指肠切除术。对于某些患有真正的中段肝外 CCA (MCC) 的患者来说，节段性胆管切除术是一种侵入性较小的替代方案。已有少量但不断增长的文献详细介绍了针对 MCC 的胆管切除术与胰十二指肠切除术或伴随肝切除术的机构经验。在此，我们简要概述了 MCC 的流行病学、术前评估和新兴的全身治疗，并叙述性回顾了比较 MCC 的节段切除术与胰十二指肠切除术或不太常见的肝切除术的现有工作，重点是手术管理和肿瘤学影响所使用的方法。© 2024。外科肿瘤学会。

Resectable cholangiocarcinoma (CCA) arising from the middle of the extrahepatic biliary tree has historically been classified as perihilar or distal CCA, depending on the operation contemplated or performed, namely the associated hepatectomy or pancreaticoduodenectomy, respectively. Segmental bile duct resection is a less invasive alternative for select patients harboring true middle extrahepatic CCA (MCC). A small, yet growing body of literature has emerged detailing institutional experiences with bile duct resection versus pancreaticoduodenectomy or concomitant hepatectomy for MCC. Herein, we provide a brief overview of the epidemiology, preoperative evaluation, and emerging systemic therapies for MCC, and narratively review the existing work comparing segmental resection with pancreaticoduodenectomy or less commonly, hepatectomy, for MCC, with emphasis on the surgical management and oncologic implications of the approach used.© 2024. Society of Surgical Oncology.