钙在心脏的电传导系统和促进心肌收缩中起着至关重要的作用。低钙血症可导致心电图检查结果，例如 QTC 间期延长，最终出现尖端扭转型室性心动过速，严重情况下可进展为心脏骤停。在 B 细胞淋巴瘤病例中，低钙血症可能由多种因素引起。肿瘤浸润可通过影响甲状旁腺或骨组织来破坏钙稳态。 B 细胞淋巴瘤中的酸中毒可导致严重的心血管不良反应。它会降低外周血管阻力和心肌收缩力，促进心律失常，并扰乱肺部的摄氧量。这些综合效应显着损害心脏功能，增加心脏骤停的可能性。这些机制需要 B 细胞淋巴瘤患者采取全面的治疗策略。在本病例报告中，我们介绍了一名 59 岁女性心脏骤停的病例，该患者患有低钙血症和继发于 B 细胞淋巴瘤的乳酸酸中毒。B 细胞淋巴瘤中的乳酸酸中毒可能是多因素造成的。促成因素包括肝乳酸清除能力障碍、肿瘤细胞代谢或氧合受损。B 细胞淋巴瘤患者可能会继发于肿瘤溶解综合征、副肿瘤综合征或继发于治疗的低钙血症。在发生心脏骤停时，应始终考虑这些可逆性原因。癌症患者。© EFIM 2024。

Calcium plays a crucial role in the heart's electrical conduction system and facilitating the contraction of cardiac muscles. Hypocalcemia can result in electrocardiogram findings such as a prolonged QTC interval and eventually torsade de pointes, which in severe cases can progress to cardiac arrest. In cases of B-cell lymphoma, hypocalcemia may arise from various factors. Tumor infiltration can disrupt calcium homeostasis by affecting the parathyroid glands or bone tissue. Acidosis in the context of B-cell lymphoma can cause significant cardiovascular adverse effects. It will reduce peripheral vascular resistance and cardiac muscle contractility, promote dysrhythmias, and disturb oxygen uptake in the lungs. These combined effects markedly compromise cardiac function, increasing the likelihood of cardiac arrest. These mechanisms necessitate comprehensive management strategies in B-cell lymphoma patients. In this case report we present a case of cardiac arrest in a 59-year-old female woman with hypocalcemia and lactic acidosis secondary to B-cell lymphoma.Lactic acidosis in B-cell lymphoma can be multifactorial. Contributing factors include inability of liver lactate clearance, tumor cell metabolism or impaired oxygenation.Patients with B-cell lymphoma may have hypocalcemia secondary to tumor lysis syndrome, paraneoplastic syndrome, or secondary to treatment.These reversible causes should always be considered in cardiac arrest in cancer patients.© EFIM 2024.