在患者可能遇到的移植后并发症中，供体来源的恶性肿瘤的传播并不常见，但可能危及生命。确定供者与受者的来源至关重要，特别是在来自供者的多个移植受者的情况下。分子生物学的进步现在可以利用常规组织样本及时且经济高效地进行准确区分。这些技术通常在医院分子生物学实验室中进行，也可在商业实验室中使用。讨论了当前的方法，并为护理实体器官接受者的临床医生提出了未来的可能性。© 2024 Wiley periodicals LLC。

Among the post-transplantation complications that patients may encounter, the transmission of a donor-derived malignant neoplasm is uncommon but potentially life threatening. The determination of donor versus recipient origin is essential particularly in the setting of multiple transplant recipients from the donor. Advances in molecular biology now allow accurate discrimination utilizing routine tissue samples in a timely and cost-effective manner. The techniques are routinely performed in hospital molecular biology laboratories and are also available in commercial labs. The current methodologies are discussed and future possibilities are presented for clinicians caring for solid organ recipients.© 2024 Wiley Periodicals LLC.