先天性角化不良是一种罕见的遗传性骨髓衰竭疾病，其特征为典型的三联征：指甲营养不良、网状皮肤色素沉着和口腔白斑。先天性角化不良患者也被描述为患有胃肠道、泌尿生殖系统、神经系统、眼科、肺部和骨骼异常。此外，80％的患者患有口腔白斑，这些区域更容易发展为口腔鳞状细胞癌。我们特此报告一例罕见的口腔鳞状细胞癌病例，患者患有先天性角化不良的年轻男性患者。版权所有 © 2024 版权所有：© 2024 印度病理学和微生物学杂志。

Dyskeratosis congenita is a rare inherited bone marrow failure disorder characterized by a classic triad: nail dystrophy, reticulate skin pigmentation, and oral leukoplakia. Patients with dyskeratosis congenita have also been described as having gastrointestinal, genitourinary, neurological, ophthalmic, pulmonary, and skeletal abnormalities. Also, 80% of patients are affected with oral leukoplakia and these areas are more prone to develop into oral squamous cell carcinoma. We hereby report a rare case of oral squamous cell carcinoma of the tongue in a young male patient with dyskeratosis congenita.Copyright © 2024 Copyright: © 2024 Indian Journal of Pathology and Microbiology.