研究动态
Articles below are published ahead of final publication in an issue. Please cite articles in the following format: authors, (year), title, journal, DOI.

天然产物治疗神经胶质瘤的潜力:关注分子机制。

Potential of Natural Products in the Treatment of Glioma: Focus on Molecular Mechanisms.

发表日期:2024 Aug 16
作者: Amirhossein Sheida, Marjan Farshadi, Amirhossein Mirzaei, Shakiba Najjar Khalilabad, Fatemeh Zarepour, Seyed Pouya Taghavi, Maryam Sadat Hosseini Khabr, Fatemeh Ravaei, Sara Rafiei, Kimia Mosadeghi, Mohammad Sepehr Yazdani, Ali Fakhraie, Alireza Ghattan, Mohammad Masoud Zamani Fard, Maryam Shahyan, Moein Rafiei, Neda Rahimian, Sayyed Alireza Talaei Zavareh, Hamed Mirzaei
来源: MOLECULAR & CELLULAR PROTEOMICS

摘要:

尽管由于可能的长期问题,传统的神经胶质瘤治疗方法逐渐减弱,但科学界重新点燃了源自自然的物质的治疗可能性。这些天然物质常见于水果和蔬菜中,被认为是药物的潜在替代品,因为先前的研究表明它们会影响癌症进展、转移、侵袭和耐药性的途径。本综述将探讨不同天然成分(如小檗碱、姜黄素、咖啡、白藜芦醇、表没食子儿茶素-3-没食子酸酯、槲皮素、丹参酮、水飞蓟素、香豆素和番茄红素)与神经胶质瘤治疗相关的分子机制。虽然含有这些化合物的均衡饮食的好处已得到广泛认可,但研究这些天然产品治疗神经胶质瘤的功效还有很大的空间。© 2024。作者获得 Springer Science Business Media, LLC 的独家许可,施普林格自然的一部分。
Despite the waning of traditional treatments for glioma due to possible long-term issues, the healing possibilities of substances derived from nature have been reignited in the scientific community. These natural substances, commonly found in fruits and vegetables, are considered potential alternatives to pharmaceuticals, as they have been shown in prior research to impact pathways surrounding cancer progression, metastases, invasion, and resistance. This review will explore the supposed molecular mechanisms of different natural components, such as berberine, curcumin, coffee, resveratrol, epigallocatechin-3-gallate, quercetin, tanshinone, silymarin, coumarin, and lycopene, concerning glioma treatment. While the benefits of a balanced diet containing these compounds are widely recognized, there is considerable scope for investigating the efficacy of these natural products in treating glioma.© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.