系统回顾和荟萃分析抗阻训练对癌症化疗患者的生活质量 (QOL)、疲劳、身体功能和肌肉力量的功效。电子数据库 PubMed、Cochrane Central、CINAHL、SCOPUS 和 Web of Science系统地检索了随机对照试验 (RCT)，这些试验比较了抗阻训练与对照训练对接受化疗的成人的生活质量、疲劳、身体功能以及下半身和上半身肌肉力量的影响。使用随机效应模型汇总标准化平均差（SMD）。使用随机试验偏倚风险工具 (RoB 2) 评估偏倚风险。纳入了 7 项随机对照试验，涉及 561 名受试者。七项 RCT 的汇总结果表明，与对照组相比，化疗期间的阻力训练显着改善了下半身力量（n = 555，SMD 0.33，95% CI 0.12 至 0.53，中等质量证据，I2 = 23%）。没有证据表明阻力训练对 QOL（n = 373，SMD 0.13，95% CI -0.15 至 0.42，低质量证据，I2 = 0%）、疲劳（n = 373，SMD -0.08，95）有影响% CI -0.37 至 0.22，低质量证据，I2 = 20%），身体功能（n = 198，SMD 0.61，95% CI -0.73 至 1.95，极低质量证据，I2 = 83%），或上限-身体力量（n = 413，SMD 0.37，95% CI -0.07至0.80，非常低质量的证据，I2 = 69%）。与对照组相比，阻力训练可以改善接受化疗的患者的下半身力量。© 2024 。 王冠。

To systematically review and meta-analyse the efficacy of resistance training on quality of life (QOL), fatigue, physical function, and muscular strength in people diagnosed with cancer undergoing chemotherapy.Electronic databases PubMed, Cochrane Central, CINAHL, SCOPUS and Web of Science were systematically searched for randomised controlled trials (RCTs) that compared the effects of resistance training to control on QOL, fatigue, physical function, and lower-body and upper-body muscular strength in adults undergoing chemotherapy. Standardised mean differences (SMDs) were pooled using a random effects model. Risk of bias was assess using the risk of bias tool for randomised trials (RoB 2).Seven RCTs encompassing 561 participants were included. The pooled results of seven RCTs showed that resistance training during chemotherapy significantly improved lower-body strength (n = 555, SMD 0.33, 95% CI 0.12 to 0.53, moderate-quality evidence, I2 = 23%) compared to control. There was no evidence for an effect of resistance training on QOL (n = 373, SMD 0.13, 95% CI -0.15 to 0.42, low-quality evidence, I2 = 0%), fatigue (n = 373, SMD -0.08, 95% CI -0.37 to 0.22, low-quality evidence, I2 = 20%), physical function (n = 198, SMD 0.61, 95% CI -0.73 to 1.95, very low-quality evidence, I2 = 83%), or upper-body strength (n = 413, SMD 0.37, 95% CI -0.07 to 0.80, very low-quality evidence, I2 = 69%).Resistance training may improve lower-body strength in patients undergoing chemotherapy treatment compared to control.© 2024. Crown.