儿童肥胖已成为全球主要的健康问题。肥胖与糖尿病、高血压、血脂异常、心血管疾病等重大健康问题有关。肥胖也被认为是假性脑瘤（PTC）的危险因素。本研究旨在探讨假性脑瘤患者体重指数（BMI）与脑脊液（CSF）压力之间的关系。共有48名诊断为PTC的儿童，年龄≤18岁，并在儿科进行随访。临床纳入回顾性研究。全国BMI百分位数曲线可供参考。我们对患者的BMI、临床和实验室结果以及脑脊液压力之间的关系进行了统计调查。在所有患者中，女性27例（56.25%），男性21例（43.75%）。就BMI百分位而言，20人（41.67%）超重或肥胖。与 BMI 在正常范围内的儿童相比，超重和肥胖患者的脑脊液压力较高 (p<<0.05)。 BMI 和 CSF 压力值之间以及单核细胞和 CSF 值之间也观察到统计学上显着的正相关性 (p<0.05)。本研究结果表明 PTC 儿童的 CSF 压力和 BMI 之间存在直接关系。超重和肥胖儿童适当的饮食、运动和药物治疗可以对PTC的治疗做出重大贡献。此外，还观察到脑脊液压力和单核细胞水平之间存在显着相关性。© 2024。作者。

Childhood obesity has become a major global health problem. Obesity is associated with major health problems, such as diabetes, hypertension, dyslipidemia, cardiovascular disease. Obesity is also considered a risk factor for Pseudotumor cerebri (PTC). The present study aimed to investigate the relationship between body mass index (BMI), and cerebrospinal fluid (CSF) pressure in patients with pseudotumor cerebri.A total of 48 children diagnosed with PTC, who were aged < 18 years and followed up in the pediatric clinic were included in the retrospective study. National BMI percentile curves were used for reference. We investigated statistically the relationship between BMI, clinical and laboratory results, and CSF pressure in patients.Of total patients 27 were female (56.25%) and 21 were male (43.75%). With regard to the BMI percentile, 20 (41.67%) were overweight or obese. CSF pressure was higher in overweight and obese patients compared to children with BMI in normal ranges (p < 0.05). A statistically significant positive correlation was also observed between BMI and CSF pressure values and between monocyte and CSF values (p < 0.05).The results of the present study indicate a direct relationship between CSF pressure and BMI in children with PTC. Appropriate diet, exercise, and medical treatment in overweight and obese children can make a significant contribution to the treatment of PTC. Additionally, a significant correlation was observed between CSF pressure and monocyte levels.© 2024. The Author(s).